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Silica Cancer du pancréas Bretagne NF-κB Ruxolitinib Arsenic Comorbidity Cancer Polycyclic aromatic hydrocarbons Dairy farmers Calcium Carcinogens Apoptosis Docking Lait AhR Drug-drug interactions Idiopathic pulmonary fibrosis Macrophages Bronchopneumopathie chronique obstructive Hypertension artérielle pulmonaire Nintedanib Fibrose pulmonaire Benzoapyrene Infection Bisphenol A Differentiation Gene expression Cigarette smoke Crystalline silica Exposition professionnelle Camp Pharmacokinetics Bacteria In vitro Pulmonary arterial hypertension Stress Immunité Whole lung lavage France Humans Toxicity Cardiovascular diseases Oxidative stress Cytokines Bactérie Efferocytosis Cytokine Polycyclic aromatic hydrocarbon Pesticides Inorganic arsenic Lung Dust exposure Toxicokinetics Chest tube drainage Regulation Genotoxicity Diesel exhaust Aryl hydrocarbon receptor Farmer Systemic sclerosis Drug transporters Environmental risk factors Interstitial lung disease Toxicité Air pollution Inflammation HepaRG cells Granulocyte-macrophage colony-stimulating factor Risque professionnel Epidemiology Inhibition Drug–drug interactions Hospital Drug transporter Hepatocyte Dendritic cells Chest tube Scleroderma Macrophage Cytochrome P450 Human hepatocytes Chronic obstructive pulmonary disease Heterocyclic amines Hepatocytes Immunotoxicity Pneumopathie infiltrante diffuse Polarization Cardiovascular GM-CSF COPD Immunity Cytochrome P-450 Detoxification Eleveurs de bétail Diesel exhaust particles Hepatoma Nrf2 Inflammatory diseases Cell signaling