Diagnosis Crystalline silica Bronchopneumopathie chronique obstructive Human hepatocytes Dendritic cells Bactérie COPD Epidemiology Arsenic Eleveurs de bétail Lung Pharmacokinetics Calcium Dairy farmers Humans Pneumopathie infiltrante diffuse Ruxolitinib Pesticides Stress Detoxification Differentiation Cardiovascular Immunotoxicity Pulmonary arterial hypertension Chest tube drainage Interstitial lung disease Diesel exhaust Comorbidity Macrophage Diesel exhaust particles Fibrose pulmonaire Bacteria GM-CSF Hepatocyte Efferocytosis Diagnostic Carcinogens Cell signaling Heterocyclic amines Environmental risk factors HepaRG cells Toxicité Risque professionnel Nrf2 Farmer Inorganic arsenic Systemic sclerosis Dust exposure Toxicokinetics Drug transporters Apoptosis Polycyclic aromatic hydrocarbons Benzoapyrene Bretagne Genotoxicity Cytochrome P-450 Hospital Cancer du pancréas Lait Acid sphingomyelinase Gene expression Toxicity Cytokines Air pollution Oxidative stress Cytokine AhR Hepatocytes Regulation Polycyclic aromatic hydrocarbon Silica Treatments Cigarette smoke Bisphenol A Polarization Pirfenidone Exposition professionnelle Hepatoma France Chest tube NF-κB Inflammation Whole lung lavage Drug–drug interactions Inhibition Camp Drug transporter Nintedanib Aryl hydrocarbon receptor Chronic obstructive pulmonary disease Drug interactions Cytochrome P450 Idiopathic pulmonary fibrosis Granulocyte-macrophage colony-stimulating factor Cardiovascular diseases Docking Cancer Scleroderma Drug-drug interactions Macrophages