Palladium-Catalyzed Cross-Coupling/Annulation Cascade for Synthesis of 9-Hydroxy and 9-Aminofluorenes
Résumé
9-Hydroxyfluorenes are easily synthesized via a tandem Suzuki/phenolic aldolisation sequence. This process was extended to 9-amino-fluorenes by simply adding various amines as third partners. X-ray structures and NMR studies confirmed the presence of intermolecular O-H center dot center dot center dot N hydrogen bonding.
Domaines
Chimie
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