Occurrence and toxicity of antimicrobial triclosan and by-products in the environment - Université de Rennes Accéder directement au contenu
Article Dans Une Revue Environmental Science and Pollution Research Année : 2012

Occurrence and toxicity of antimicrobial triclosan and by-products in the environment

Résumé

Introduction and aims A review was undertaken on the occurrence, toxicity, and degradation of triclosan (TCS; 5-chloro-2,4-dichlorophenoxy)phenol) in the environment. TCS is a synthetic, broad-spectrum antibacterial agent incorporated in a wide variety of household and personal care products such as hand soap, toothpaste, and deodorants but also in textile fibers used in a range of other consumer products (e.g., toys, undergarments and cutting boards among other things). Occurrence Because of its partial elimination in sewage treatment plants, most reports describe TCS as one of the most commonly encountered substances in solid and water environmental compartments. It has been detected in a microgram per liter or microgram per kilogram level in sewage treatment plants (influents, effluents, and sludges), natural waters (rivers, lakes, and estuarine waters), and sediments as well as in drinking water. Toxicity Moreover, due to its high hydrophobicity, TCS can accumulate in fatty tissues and has been found in fish and human samples (urine, breast milk, and serum). TCS is known to be biodegradable, photo-unstable, and reactive towards chlorine and ozone. Discussion As a consequence, it can be transformed into potentially more toxic and persistent compounds, such as chlorinated phenols and biphenyl ethers after chlorination, methyl triclosan after biological methylation, and chlorinated dibenzodioxins after photooxidation. The toxicity of TCS toward aquatic organisms like fish, crustaceans, and algae has been demonstrated with EC50 values near TCS environmental concentrations. It has even been shown to produce cytotoxic, genotoxic, and endocrine disruptor effects. Conclusion Furthermore, the excessive use of TCS is suspected to increase the risk of emergence of TCS-resistant bacteria and the selection of resistant strains.

Dates et versions

hal-00716307 , version 1 (10-07-2012)

Identifiants

Citer

G. Bedoux, B. Roig, Olivier Thomas, V. Dupont, Barbara Le Bot. Occurrence and toxicity of antimicrobial triclosan and by-products in the environment. Environmental Science and Pollution Research, 2012, 19 (4), pp.1044-65. ⟨10.1007/s11356-011-0632-z⟩. ⟨hal-00716307⟩
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