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Journal Articles Letters in Organic Chemistry Year : 2013

Synthesis of New 3-heteroaryl-2-phenylquinolines and their Pharmacological Activity as Antimicrobial Agents

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Abstract

Some new unfused tricyclic aromatic systems containing various heterocyclic cores were synthesized. These compounds were prepared in good yields via appropriate routes using 6-methyl-2-phenylquinoline-3-carbaldehyde as a key intermediate. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia and Salmonella thipymurium using the disk-diffusion method. The minimum inhibitory concentration (MIC) was determined for the tested compounds.
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hal-00871959 , version 1 (11-10-2013)

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Saida Benzerka, Abdelmalek Bouraiou, Sofiane Bouacida, Thierry Roisnel, Chafia Bentchouala, et al.. Synthesis of New 3-heteroaryl-2-phenylquinolines and their Pharmacological Activity as Antimicrobial Agents. Letters in Organic Chemistry, 2013, 10 (2), pp.94-99. ⟨10.2174/1570178611310020005⟩. ⟨hal-00871959⟩
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