Fusion of MSCT imaging, Electro-Anatomical Mapping and Speckle Tracking Echocardiography for the characterization of local electro-mechanical delays in CRT optimization.

François Tavard (1) , Antoine Simon (1) , Erwan Donal (2) , Alfredo I. Hernández (2) , Mireille Garreau (2)

1 LTSI - Laboratoire Traitement du Signal et de l'Image
2 LTSI - Laboratoire Traitement du Signal et de l'Image

In this work, we sought to assist the optimization of Cardiac Resynchronization Therapy (CRT) through the characterization of electro-mechanical delays for each region of the Left Ventricle. This characterization is based on the fusion of electrical, mechanical and anatomical data acquired from Electro-Anatomical Mapping (EAM), Speckle Tracking Echocardiography (STE) and Multislice CT (MSCT) imaging, respectively. Using MSCT as a reference, the first step is the registration of EAM 3D maps and STE 2D Contours on extracted MSCT LV-surfaces. After this registration step, local electrical and mechanical activation times can be displayed in the same space through 2D quantitative maps, therefore allowing the computation of local electro-mechanical delays. Local and global electro-mechanical delays from septal and lateral walls were calculated for three patients. The complementary information obtained may be useful for a better patient selection for CRT.

Mots clés: computerised tomography; echocardiography; image fusion; image registration; medical image processing

Domaines: Ingénierie biomédicale; Traitement du signal et de l'image [eess.SP]; Traitement du signal et de l'image [eess.SP]; Cardiologie et système cardiovasculaire

François Tavard, Antoine Simon, Erwan Donal, Alfredo I. Hernández, Mireille Garreau. Fusion of MSCT imaging, Electro-Anatomical Mapping and Speckle Tracking Echocardiography for the characterization of local electro-mechanical delays in CRT optimization.. IEEE Computing in Cardiology, Sep 2010, Belfast, Ireland. pp.401 - 404. ⟨hal-00910921⟩