Skip to Main content Skip to Navigation
Journal articles

Regio- and stereocontrolled access to γ-boronated unsaturated amino esters and derivatives from (Z)-alkenyl 1,2-bis(boronates).

Abstract : The Borono-Mannich reaction of (Z)-1-alkene-1,2-diboronic esters proceeded regioselectively at the terminal C-B bond to afford (E)-γ-boronated unsaturated amino esters in good yields. These compounds were then subjected to Suzuki couplings for the creation of diversely substituted olefinic amino acid systems. Several other functional transformations were also carried out to illustrate the synthetic utility of the Petasis products.
Document type :
Journal articles
Complete list of metadatas

https://hal-univ-rennes1.archives-ouvertes.fr/hal-00955530
Contributor : Bertrand Carboni <>
Submitted on : Tuesday, March 4, 2014 - 4:08:54 PM
Last modification on : Thursday, March 5, 2020 - 2:05:19 PM

Identifiers

Citation

Tailor Sridhar, Fabienne Berrée, Gangavaram V M Sharma, Bertrand Carboni. Regio- and stereocontrolled access to γ-boronated unsaturated amino esters and derivatives from (Z)-alkenyl 1,2-bis(boronates).. Journal of Organic Chemistry, American Chemical Society, 2014, 79 (2), pp.783-9. ⟨10.1021/jo402237t⟩. ⟨hal-00955530⟩

Share

Metrics

Record views

225