M. J. Amorim, J. R?mbke, and A. M. Soares, Avoidance behaviour of Enchytraeus 582 albidus: Effects of Benomyl, Carbendazim, phenmedipham and different soil types, Chemosphere, vol.59, pp.583-501, 2005.

M. P. Anderson and J. W. Gronwald, Atrazine Resistance in a Velvetleaf (Abutilon 585 theophrasti) Biotype Due to Enhanced Glutathione S-Transferase Activity, Plant Physiol, vol.586, pp.96-104, 1991.

F. Binet, L. Fayolle, M. Pussard, J. J. Crawford, S. J. Traina et al., Significance of earthworms in stimulating soil microbial activity, Biology and Fertility of Soils, vol.27, issue.1, pp.79-84, 1998.
DOI : 10.1007/s003740050403

L. Dendooven, G. Peres, J. E. Tondoh, D. Cluzeau, and J. Brun, A review of 595 earthworm impact on soil function and ecosystem services, Eur. J. Soil Sci, vol.64, pp.161-182, 2013.

P. Jouquet, Earthworms accelerate soil porosity turnover under watering 598 conditions, Geoderma, vol.156, pp.43-47, 2010.

M. M. Bradford, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Analytical Biochemistry, vol.72, issue.1-2, pp.248-254, 1976.
DOI : 10.1016/0003-2697(76)90527-3

J. M. Brausch and P. N. Smith, Pesticide resistance from historical agricultural chemical exposure in Thamnocephalus platyurus (Crustacea: Anostraca), Environmental Pollution, vol.157, issue.2, pp.481-487, 2009.
DOI : 10.1016/j.envpol.2008.09.010

R. H. Bromilow, A. A. Evans, and P. H. Nicholls, Factors affecting degradation rates of five triazole fungicides in two soil types: 2. Field studies, Pesticide Science, vol.38, issue.124, pp.1135-1142, 1999.
DOI : 10.1002/(SICI)1096-9063(199912)55:12<1135::AID-PS73>3.0.CO;2-1

R. H. Bromilow, A. A. Evans, and P. H. Nicholls, Factors affecting degradation rates of 608 five triazole fungicides in two soil types: 1. Laboratory incubations, Pestic. Sci, vol.55, pp.1129-609, 1999.

S. A. Brown, J. R. Mckelvie, A. J. Simpson, and M. J. Simpson, 1H NMR metabolomics of 611 earthworm exposure to sub-lethal concentrations of phenanthrene in soil. Environ. 612 Pollut, pp.2117-2123, 2010.

J. Bundy, J. Sidhu, F. Rana, D. Spurgeon, C. Svendsen et al., Systems toxicology approach identifies coordinated metabolic 615 responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus 616 rubellus, BMC Biol, vol.8, issue.25, p.617

P. Calow, Physiological costs of combating chemical toxicants: Ecological implications, Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, vol.100, issue.1-2, pp.3-6, 1991.
DOI : 10.1016/0742-8413(91)90110-F

Y. Capowiez and A. Bérard, Assessment of the effects of imidacloprid on the behavior of two earthworm species (Aporrectodea nocturna and Allolobophora icterica) using 2D terraria, Ecotoxicology and Environmental Safety, vol.64, issue.2, pp.198-206, 2006.
DOI : 10.1016/j.ecoenv.2005.02.013

Y. Capowiez, N. Dittbrenner, M. Rault, R. Triebskorn, M. Hedde et al., Earthworm cast production as a new behavioural biomarker for toxicity testing, Environmental Pollution, vol.158, issue.2, pp.388-393, 0624.
DOI : 10.1016/j.envpol.2009.09.003

T. Decaëns and J. J. Jiménez, Earthworm communities under an agricultural 626 intensification gradient in Colombia, Plant and Soil, vol.240, issue.1, pp.133-143, 2002.
DOI : 10.1023/A:1015844610604

N. Dittbrenner, R. Triebskorn, I. Moser, and Y. Capowiez, Physiological and behavioural effects of imidacloprid on two ecologically relevant earthworm species (Lumbricus terrestris and Aporrectodea caliginosa), Ecotoxicology, vol.12, issue.8, pp.1567-1573, 2010.
DOI : 10.1007/s10646-010-0542-8

M. H. Donker, C. Zonneveld, and N. M. Straalen, Early reproduction and increased reproductive allocation in metal-adapted populations of the terrestrial isopod Porcellio scaber, Oecologia, vol.3, issue.3, pp.316-323, 1993.
DOI : 10.1007/BF00317500

A. Farenhorst, E. Topp, B. Bowman, and A. Tomlin, Earthworm burrowing and feeding activity and the potential for atrazine transport by preferential flow, Soil Biology and Biochemistry, vol.32, issue.4, pp.479-488, 2000.
DOI : 10.1016/S0038-0717(99)00177-7

K. V. Fisker, J. G. Sørensen, C. Damgaard, K. L. Pedersen, and M. Holmstrup, Genetic adaptation of earthworms to copper pollution: is adaptation associated with fitness costs in Dendrobaena octaedra?, Ecotoxicology, vol.37, issue.11, pp.563-573, 2011.
DOI : 10.1007/s10646-011-0610-8

J. Folch, M. Lees, and G. H. Sloane-stanley, A simple method for the isolation and 642 purification of total lipids from animal tissues, J. Biol. Chem, vol.226, pp.497-509, 1957.

D. Fournier and A. Mutero, Modification of acetylcholinesterase as a mechanism of 644 resistance to insecticides, Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol, vol.645, issue.108, pp.19-31, 1994.

B. Gevao, K. T. Semple, and K. C. Jones, Bound pesticide residues in soils: a review, Environmental Pollution, vol.108, issue.1, pp.3-14, 2000.
DOI : 10.1016/S0269-7491(99)00197-9

M. D. Groppa and M. P. Benavides, Polyamines and abiotic stress: recent advances, Amino Acids, vol.139, issue.1, p.649, 2008.
DOI : 10.1007/s00726-007-0501-8

M. Gudbrandsen, L. E. Sverdrup, S. Aamodt, and J. Stenersen, Short-term pre-exposure increases earthworm tolerance to mercury, European Journal of Soil Biology, vol.43, pp.261-267, 2007.
DOI : 10.1016/j.ejsobi.2007.08.025

S. K. Gupta and V. Sundararaman, Correlation between burrowing capability and AChE activity in the earthworm,Pheretima posthuma, on exposure to carbaryl, Bulletin of Environmental Contamination and Toxicology, vol.10, issue.6, pp.859-865, 1991.
DOI : 10.1007/BF01689730

K. V. Fisker, K. Maraldo, D. Waagner, R. Labouriau, and G. Asmund, Body metal 660 concentrations and glycogen reserves in earthworms (Dendrobaena octaedra) from 661 contaminated and uncontaminated forest soil, Environ. Pollut, vol.159, pp.190-197, 2011.

M. S. Hugnes, C. M. Bull, and B. M. Doube, Microcosm investigations into the influence of sheep manure on the behaviour of the geophagous earthworms Aporrectodea trapezoides and Microscolex dubuis, Biology and Fertility of Soils, vol.12, issue.1-2, pp.71-75, 1996.
DOI : 10.1007/BF00384435

M. Jansen, A. Coors, R. Stoks, and L. De-meester, Evolutionary ecotoxicology of pesticide resistance: a case study in Daphnia, Ecotoxicology, vol.277, issue.113, pp.543-551, 2011.
DOI : 10.1007/s10646-011-0627-z

C. G. Jones, J. H. Lawton, and M. Shachak, POSITIVE AND NEGATIVE EFFECTS OF ORGANISMS AS PHYSICAL ECOSYSTEM ENGINEERS, Ecology, vol.78, issue.7, pp.1946-1957, 1997.
DOI : 10.2307/1940449

D. Jordan, R. Miles, V. Hubbard, and T. Lorenz, Effect of management practices and cropping systems on earthworm abundance and microbial activity in Sanborn Field: a 115-year-old agricultural field, Pedobiologia, vol.48, issue.2, pp.99-110, 2004.
DOI : 10.1016/j.pedobi.2003.06.001

M. Kanehisa and S. Goto, KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic 673 Acids Res, pp.27-30, 2000.

S. Khodayari, S. Moharramipour, V. Larvor, K. Hidalgo, and D. Renault, Deciphering the Metabolic Changes Associated with Diapause Syndrome and Cold Acclimation in the Two-Spotted Spider Mite Tetranychus urticae, PLoS ONE, vol.94, issue.1, pp.54025-677, 2013.
DOI : 10.1371/journal.pone.0054025.s002

URL : https://hal.archives-ouvertes.fr/hal-00812070

J. Krasensky and C. Jonak, Drought, salt, and temperature stress-induced metabolic rearrangements and regulatory networks, Journal of Experimental Botany, vol.63, issue.4, pp.1593-1608, 2012.
DOI : 10.1093/jxb/err460

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359903

M. Lamandé, V. Hallaire, P. Curmi, G. Pérès, and D. Cluzeau, Changes of pore morphology, infiltration and earthworm community in a loamy soil under different agricultural managements, CATENA, vol.54, issue.3, pp.637-649, 2003.
DOI : 10.1016/S0341-8162(03)00114-0

B. Lankadurai, E. Nagato, and M. Simpson, Environmental Metabolomics: An 683 Emerging Approach to Study Organism Responses to Environmental Stressors. Environ. 684 Rev, p.685, 2013.

H. Liang, J. Qiu, L. Li, W. Li, Z. Zhou et al., Stereoselective dissipation of 688 epoxiconazole in grape (Vitis vinifera cv. Kyoho) and soil under field conditions, Chemosphere, vol.87, pp.689-982, 2012.

Y. Liu, A. Zaprasis, S. Liu, H. L. Drake, and M. A. Horn, The earthworm 691, 2011.

T. Lukkari, M. Taavitsainen, M. Soimasuo, A. Oikari, and J. Haimi, Biomarker 694 responses of the earthworm Aporrectodea tuberculata to copper and zinc exposure: 695 differences between populations with and without earlier metal exposure. Environ. 696 Pollut, pp.377-386, 2004.

C. Monard, F. Martin-laurent, C. Vecchiato, A. J. Francez, and P. Vandenkoornhuyse, Combined effect of bioaugmentation and bioturbation on atrazine degradation in soil, Soil Biology and Biochemistry, vol.40, issue.9, pp.2253-2259, 2008.
DOI : 10.1016/j.soilbio.2008.04.022

URL : https://hal.archives-ouvertes.fr/hal-00336008

C. Monard, P. Vandenkoornhuyse, L. Bot, B. Binet, and F. , Relationship between bacterial diversity and function under biotic control: the soil pesticide degraders as a case study, The ISME Journal, vol.53, issue.6, pp.1048-1056, 2011.
DOI : 10.1073/pnas.96.4.1463

URL : https://hal.archives-ouvertes.fr/hal-00651076

C. J. Mordaunt, B. Gevao, K. C. Jones, and K. T. Semple, Formation of non-extractable pesticide residues: observations on compound differences, measurement and regulatory issues, Environmental Pollution, vol.133, issue.1, pp.25-34, 2005.
DOI : 10.1016/j.envpol.2004.04.018

V. Nuutinen, Earthworm community response to tillage and residue management on different soil types in southern Finland, Soil and Tillage Research, vol.23, issue.3, pp.221-239, 1992.
DOI : 10.1016/0167-1987(92)90102-H

M. G. Paoletti, The role of earthworms for assessment of sustainability and as bioindicators, Agriculture, Ecosystems & Environment, vol.74, issue.1-3, pp.137-155, 1999.
DOI : 10.1016/S0167-8809(99)00034-1

E. Passeport, P. Benoit, V. Bergheaud, Y. Coquet, and J. Tournebize, Epoxiconazole degradation from artificial wetland and forest buffer substrates under flooded conditions, Chemical Engineering Journal, vol.173, issue.3, pp.760-765, 2011.
DOI : 10.1016/j.cej.2011.08.044

URL : https://hal.archives-ouvertes.fr/hal-01003237

C. Pelosi, S. Barot, Y. Capowiez, M. Hedde, and F. Vandenbulcke, Pesticides and 717 earthworms. A review, Agron. Sustain. Dev, pp.1-30, 2013.
DOI : 10.1007/s13593-013-0151-z

URL : http://dx.doi.org/10.1007/s13593-013-0151-z

C. Pook, C. Lewis, and T. Galloway, The metabolic and fitness costs associated with metal resistance in Nereis diversicolor, Marine Pollution Bulletin, vol.58, issue.7, pp.1063-1071, 2009.
DOI : 10.1016/j.marpolbul.2009.02.003

L. Posthuma, Genetic Differentiation Between Populations of Orchesella cincta (Collembola) from Heavy Metal Contaminated Sites, The Journal of Applied Ecology, vol.27, issue.2, pp.609-622, 1990.
DOI : 10.2307/2404306

L. Posthuma and N. M. Van-straalen, Heavy-metal adaptation in terrestrial 723 invertebrates: A review of occurrence, genetics, physiology and ecological consequences, p.724, 1993.

. Comp, 725 R Development Core Team R: A language and environment for statistical 726 computing. R Foundation for Statistical Computing, Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol, vol.106, pp.11-38, 2008.

H. J. Rhee, E. Kim, and J. K. Lee, Physiological polyamines: simple primordial stress molecules, Journal of Cellular and Molecular Medicine, vol.168, issue.4, pp.685-703, 2007.
DOI : 10.1104/pp.009951

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823250

D. Ribera, J. F. Narbonne, C. Arnaud, and M. Saint-denis, Biochemical responses of the earthworm Eisenia fetida andrei exposed to contaminated artificial soil, effects of carbaryl, Soil Biology and Biochemistry, vol.33, issue.7-8, pp.1123-1130, 2001.
DOI : 10.1016/S0038-0717(01)00035-9

L. Rodríguez-castellanos and J. C. Sanchez-hernandez, Earthworm biomarkers of pesticide contamination: Current status and perspectives, Journal of Pesticide Science, vol.32, issue.4, pp.360-371, 2007.
DOI : 10.1584/jpestics.R07-14

E. Schreck, F. Geret, L. Gontier, and M. Treilhou, Neurotoxic effect and metabolic responses induced by a mixture of six pesticides on the earthworm Aporrectodea caliginosa nocturna, Chemosphere, vol.71, issue.10, pp.1832-1839, 2008.
DOI : 10.1016/j.chemosphere.2008.02.003

M. J. Simpson, J. R. Mckelvie, C. P. Mcswiney, A. S. Grandy, P. Suwanwaree et al., Environmental metabolomics: new insights into earthworm ecotoxicity and contaminant bioavailability in soil, Analytical and Bioanalytical Chemistry, vol.3, issue.141, pp.137-149, 2008.
DOI : 10.1007/s00216-009-2612-4

W. Söchtig and O. Larink, Effect of soil compaction on activity and biomass of endogeic lumbricids in arable soils, Soil Biology and Biochemistry, vol.24, issue.12, pp.1595-1599, 1992.
DOI : 10.1016/0038-0717(92)90156-R

J. A. Springett and R. A. Gray, Effect of repeated low doses of biocides on the earthworm Aporrectodea caliginosa in laboratory culture, Soil Biology and Biochemistry, vol.24, issue.12, pp.1739-747, 1992.
DOI : 10.1016/0038-0717(92)90180-6

A. R. Thompson, Effects of nine insecticides on the numbers and biomass of earthworms in pasture, Bulletin of Environmental Contamination and Toxicology, vol.38, issue.6, pp.577-586, 1971.
DOI : 10.1007/BF01539990

C. Wiegand, S. Pehkonen, J. Akkanen, O. Penttinen, and J. V. Kukkonen, Bioaccumulation of paraquat by Lumbriculus variegatus in the presence of dissolved natural organic matter and impact on energy costs, biotransformation and antioxidative enzymes, Chemosphere, vol.66, issue.3, pp.558-566, 2007.
DOI : 10.1016/j.chemosphere.2006.05.048

C. Wiegand, S. Pflugmacher, M. Giese, H. Frank, and C. Steinberg, Uptake, Toxicity, and Effects on Detoxication Enzymes of Atrazine and Trifluoroacetate in Embryos of Zebrafish, Ecotoxicology and Environmental Safety, vol.45, issue.2, pp.122-131, 2000.
DOI : 10.1006/eesa.1999.1845

S. Yasmin and D. Souza, Effects of Pesticides on the Growth and Reproduction of profiles and epoxiconazole exposure along time. A, B: Scores plots for conventional population, p.817