Metabolism of polycyclic aromatic hydrocarbons : etiologic roles in carcinogenesis, Pharmacol. Rev, vol.34, pp.189-222, 1982. ,
Meta-analysis of epidemiologic studies on cigarette smoking and liver cancer, International Journal of Epidemiology, vol.38, issue.6, pp.1487-1511, 2009. ,
DOI : 10.1093/ije/dyp280
Polycyclic aromatic hydrocarbon-DNA adducts in liver tissues of hepatocellular carcinoma patients and controls, International Journal of Cancer, vol.24, issue.1, pp.14-21, 2002. ,
DOI : 10.1002/ijc.10291
Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates, Carcinogenesis, vol.22, issue.12, pp.1903-1930, 2001. ,
DOI : 10.1093/carcin/22.12.1903
Dioxin suppresses benzo[a]pyrene-induced mutations and DNA adduct formation through cytochrome P450 1A1 induction and (??)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide inactivation in human hepatoma cells, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol.750, issue.1-2, pp.77-85, 2013. ,
DOI : 10.1016/j.mrgentox.2012.09.008
Dietary polyphenols protect against N-nitrosamines and benzo(a)pyrene-induced DNA damage (strand breaks and oxidized purines/pyrimidines) in HepG2 human hepatoma cells, European Journal of Nutrition, vol.38, issue.8, pp.479-490, 2008. ,
DOI : 10.1007/s00394-008-0751-6
Multiple apoptotic pathways induced by p53-dependent acidification in benzo[a]pyrene-exposed hepatic F258 cells, J. Cell. Physiol, vol.2083, pp.527-564, 2006. ,
URL : https://hal.archives-ouvertes.fr/inserm-00130324
Role of cell signaling involved in induction of apoptosis by benzo[a]pyrene and cyclopenta[c,d]pyrene in Hepa1C1C7 cells, J. Cell ,
Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice, Hepatology, vol.51, pp.1226-1236, 2010. ,
PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice, Hepatology, vol.11, issue.Suppl. 1, pp.1249-1258, 2011. ,
DOI : 10.1002/hep.24516
Conflicting Roles of Molecules in Hepatocarcinogenesis: Paradigm or Paradox, Cancer Cell, vol.21, issue.2 ,
DOI : 10.1016/j.ccr.2012.01.001
Identification of Na+/H+ exchange as a new target for toxic polycyclic aromatic hydrocarbons, Faseb J, vol.287, pp.844-850, 2004. ,
Protective effect of monosialoganglioside GM1 against chemically induced apoptosis through targeting of mitochondrial function and iron transport, Biochem ,
URL : https://hal.archives-ouvertes.fr/hal-00699820
Membrane fluidity changes are associated with benzo[a]pyrene-induced apoptosis in F258 cells : protection by exogenous cholesterol, p.26 ,
URL : https://hal.archives-ouvertes.fr/hal-00699948
Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis, Toxicol. Appl. Pharmacol, vol.243, pp.68-76, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00729575
NHE-1 relocation outside cholesterol-rich membrane microdomains is associated with its benzo[a]pyrene-related apoptotic function, Cell. Physiol. Biochem, vol.29, pp.657-666, 2012. ,
URL : https://hal.archives-ouvertes.fr/inserm-00871487
Physical and chemical modulation of lipid rafts by a dietary n-3 polyunsaturated fatty acid increases ethanol-induced oxidative stress. Free Radic, Biol. Med, vol.51, pp.2018-2030, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00695247
Tobacco smoking, alcohol consumption and their interaction in the causation of hepatocellular carcinoma, Int. J. Cancer, vol.85, pp.498-502, 2000. ,
Influences of tobacco and alcohol use on hepatocellular carcinoma survival, International Journal of Cancer, vol.162, issue.5 Suppl 1, p.27 ,
DOI : 10.1002/ijc.27508
Roles of alcohol and tobacco exposure in the development of hepatocellular carcinoma, Life Sciences, vol.92, issue.1, pp.3-9, 2013. ,
DOI : 10.1016/j.lfs.2012.10.009
Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type, Experimental Cell Research, vol.143, issue.1, pp.47-54, 1983. ,
DOI : 10.1016/0014-4827(83)90107-6
Lagadic-Gossmann, D. Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells, Chem. Biol. Interact, vol.167, pp.41-55, 2007. ,
Liver protection from apoptosis requires both blockage of initiator caspase activities and inhibition of ASK1/JNK pathway via glutathione S-transferase regulation, J. Biol. Chem, vol.277, pp.49220-49229, 2002. ,
Fluorescence probes used for detection of reactive oxygen species, Journal of Biochemical and Biophysical Methods, vol.65, issue.2-3, pp.45-80, 2005. ,
DOI : 10.1016/j.jbbm.2005.10.003
EPR determination of low molecular weight iron content applied to whole rat hepatocytes, Cell ,
The Role of Iron in Oxygen-Mediated Toxicities, Critical Reviews in Toxicology, vol.10, issue.2, pp.119-141, 1992. ,
DOI : 10.1172/JCI112349
Lagadic-Gossmann, D. A new lactoferrin-and irondependent lysosomal death pathway is induced by benzo, hepatic epithelial cells ,
Lipid Raft Redox Signaling: Molecular Mechanisms in Health and Disease, Antioxidants & Redox Signaling, vol.15, issue.4, pp.1043-1083, 2011. ,
DOI : 10.1089/ars.2010.3619
Lysosomal Iron, Iron Chelation, and Cell Death, Antioxidants & Redox Signaling, vol.18, issue.8, pp.888-898, 2013. ,
DOI : 10.1089/ars.2012.4885
Bax inhibition protects against free fatty acid-induced lysosomal permeabilization, AJP: Gastrointestinal and Liver Physiology, vol.290, issue.6 ,
DOI : 10.1152/ajpgi.00509.2005
Oxidative stress causes a decline in lysosomal integrity during hypothermic incubation of rat hepatocytes, Free Radical Biology and Medicine, vol.44, issue.1 ,
DOI : 10.1016/j.freeradbiomed.2007.09.003
Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization. Free Radic, Biol. Med, vol.50, pp.281-294, 2011. ,
Sensitivity to lysosome-dependent cell death is directly regulated by lysosomal 29 ,
Aryl Hydrocarbon Receptor Modulation of Tumor Necrosis Factor-??-induced Apoptosis and Lysosomal Disruption in a Hepatoma Model That Is Caspase-8-independent, Journal of Biological Chemistry, vol.281, issue.16, pp.10954-67, 2006. ,
DOI : 10.1074/jbc.M508383200
Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent manner, Hepatology, vol.23, issue.Suppl, 1994. ,
DOI : 10.1002/hep.25571
Lysosomal membrane permeabilization in cell death, Oncogene, vol.283, issue.50, pp.6434-6451, 2008. ,
DOI : 10.1002/dvdy.21076
Cathepsins: Key modulators of cell death and inflammatory responses, Biochemical Pharmacology, vol.76, issue.11, pp.1374-1382, 2008. ,
DOI : 10.1016/j.bcp.2008.07.041
Lysosomal???mitochondrial cross-talk during cell death, Mitochondrion, vol.10, issue.6 ,
DOI : 10.1016/j.mito.2010.07.008