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A new and efficient one-pot synthesis of 2-hydroxy-1,4-dihydrobenzoxazines via a three-component Petasis reaction

Abstract : The secondary amines synthesized by the reaction between 2-aminophenols and aromatic aldehydes, via the reduction of the corresponding imines, were employed in the synthesis of new 2-hydroxy-2H-1,4-benzoxazine derivatives via a one-pot Petasis multicomponent reaction in good to excellent yields.
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Submitted on : Monday, November 3, 2014 - 3:33:40 PM
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Louisa Chouguiat, Raouf Boulcina, Bertrand Carboni, Albert Demonceau, Abdelmadjid Debache. A new and efficient one-pot synthesis of 2-hydroxy-1,4-dihydrobenzoxazines via a three-component Petasis reaction. Tetrahedron Letters, Elsevier, 2014, 55 (37), pp.5124-5128. ⟨10.1016/j.tetlet.2014.07.093⟩. ⟨hal-01079729⟩

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