Skip to Main content Skip to Navigation
Journal articles

Total synthesis of (-)-epimyrtine by a gold-catalyzed hydroamination approach.

Abstract : A new approach to the total synthesis of (-)-epimyrtine has been developed from D-alanine. The key step to access the enantiopure pyridone intermediate was achieved by a gold-mediated cyclization. Finally, various transformations afforded the natural product in a few steps and good overall yield.
Document type :
Journal articles
Complete list of metadata
Contributor : Laurent Jonchère Connect in order to contact the contributor
Submitted on : Thursday, February 12, 2015 - 4:35:41 PM
Last modification on : Monday, June 27, 2022 - 1:20:41 PM

Links full text



Thi Thanh Huyen Trinh, Khanh Hung Nguyen, Patricia de Aguiar Amaral, Nicolas Gouault. Total synthesis of (-)-epimyrtine by a gold-catalyzed hydroamination approach.. Beilstein Journal of Organic Chemistry, Beilstein-Institut, 2012, 9, pp.2042-7. ⟨10.3762/bjoc.9.242⟩. ⟨hal-01116168⟩



Record views