Anti-glomerular basement membrane disease, ulcerative colitis, and primary sclerosing cholangitis: link or co-incidence? - Archive ouverte HAL Access content directly
Journal Articles Nephrology Reviews Year : 2010

Anti-glomerular basement membrane disease, ulcerative colitis, and primary sclerosing cholangitis: link or co-incidence?

Abstract

Ulcerative colitis, primary sclerosing cholangitis, and anti-glomerular basement membrane disease (anti-GBM) are three rare immune diseases with incompletely under-stood pathogenic mechanisms. We describe here the case of a 29-year-old man with ulcer-ative colitis and primary sclerosing cholang -itis who, eight years later, developed anti-GBM disease with destruction of all glomeruli leading to end-stage kidney disease. Association of these three immune diseases in the same patient has never been described. Because HLA-mediated susceptibility cannot be incriminated completely in our case, we hypothesize that environmental factors or previous immunosuppressive treatment used might be the link.
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Dates and versions

hal-01117592 , version 1 (17-02-2015)

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Attribution - NonCommercial - NoDerivatives - CC BY 4.0

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Emilie Pinçon, Guillaume Bouguen, Guillaume Coiffier, Joseph Rivalan, Patrick Le Pogamp, et al.. Anti-glomerular basement membrane disease, ulcerative colitis, and primary sclerosing cholangitis: link or co-incidence?. Nephrology Reviews, 2010, 2 (1), pp.47-48. ⟨10.4081/nr.2010.e10⟩. ⟨hal-01117592⟩
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