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Docetaxel-induced photo-recall phenomenon.

Abstract : Photo-recall phenomenon is a phototoxic eruption occurring on areas of previous ultraviolet-induced solar erythema following a systemic administration of a drug. It has been mostly described with methotrexate but remains rare with other antineoplastic drugs. We describe a case of docetaxel-induced photo-recall skin rash in a woman treated for a non-small-cell lung cancer. Although the patient has refused to receive a second infusion, chemotherapy can be carried on with photoprotection and the use of topical and/or systemic corticosteroids. In contrast, radiation recall is a well-known reaction by oncologists, most of them may not be aware of a similar phenomenon called photo-recall phenomenon. Recognizing this entity may avoid misdiagnosing a drug allergy and should avoid inappropriate decisions of drug discontinuation.
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Contributor : Laurent Jonchère <>
Submitted on : Thursday, February 26, 2015 - 12:52:57 PM
Last modification on : Thursday, January 14, 2021 - 11:15:59 AM

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Catherine Droitcourt, Hélêne Le Hô, Henri Adamski, François Le Gall, Alain Dupuy. Docetaxel-induced photo-recall phenomenon.. Photodermatology, Photoimmunology & Photomedicine, Wiley, 2012, 28 (4), pp.222-3. ⟨10.1111/j.1600-0781.2012.00669.x⟩. ⟨hal-01120678⟩



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