First Case of Disseminated Infection with Nocardia cerradoensis in a Human.

Caroline Piau , Mallorie Kerjouan (1) , Marc Le Mouel , Solene Patrat-Delon (2) , Pierre-Louis Henaux (3) , Vanessa Brun , Marie-Pascale Morin , Philippe Gautier , Veronica Rodriguez-Nava (4) , Samer Kayal (5)

1 Service de pneumologie [Rennes] = Pneumology [Rennes]
2 Irset - Institut de recherche en santé, environnement et travail
3 Service de neurochirurgie [Rennes] = Neurosurgery [Rennes]
4 LEM - Laboratoire d'Ecologie Microbienne - UMR 5557
5 IGDR - Institut de Génétique et Développement de Rennes

Here we report in a human, a renal transplant patient, the first disseminated infection with Nocardia cerradoensis, isolated after a brain biopsy. Species identification was based on 16S rRNA, gyrB, and hsp65 gene analyses. Antibiotic treatment was successful by combining carbapenems and aminoglycosides and then switching to oral trimethoprim-sulfamethoxazole.

Domains: Life Sciences [q-bio]

Caroline Piau, Mallorie Kerjouan, Marc Le Mouel, Solene Patrat-Delon, Pierre-Louis Henaux, et al.. First Case of Disseminated Infection with Nocardia cerradoensis in a Human.. Journal of Clinical Microbiology, 2015, 53 (3), pp.1034-7. ⟨10.1128/JCM.02979-14⟩. ⟨hal-01130428⟩