Pglycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes, Drug Metab Dispos, vol.29, pp.1277-1283, 2001. ,
In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation, Drug Metabolism and Disposition, vol.40, issue.6, pp.1085-1092, 2012. ,
DOI : 10.1124/dmd.111.043489
In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development, Clinical Pharmacology & Therapeutics, vol.43, issue.1, pp.95-112, 2013. ,
DOI : 10.1093/toxsci/kfq269
Characterization of increased drug metabolism activity in dimethyl sulfoxide (DMSO)-treated Huh7 hepatoma cells, Xenobiotica, vol.102, issue.3, pp.205-217, 2009. ,
DOI : 10.1517/17425255.2.6.875
A Short N-Proximal Region in the Large Envelope Protein Harbors a Determinant That Contributes to the Species Specificity of Human Hepatitis B Virus, Journal of Virology, vol.75, issue.23, pp.11565-11572, 2001. ,
DOI : 10.1128/JVI.75.23.11565-11572.2001
exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity, Expert Opinion on Drug Metabolism & Toxicology, vol.92, issue.6, pp.589-616, 2013. ,
DOI : 10.1124/dmd.112.047225
Detection of P glycoprotein activity on normal and leukemic CD34+ cells, Leukemia Research, vol.17, issue.12, pp.1031-1035, 1993. ,
DOI : 10.1016/0145-2126(93)90159-I
Quantification of biliary excretion and sinusoidal excretion of 5(6)-carboxy-2???,7???-dichlorofluorescein (CDF) in cultured hepatocytes isolated from Sprague Dawley, Wistar and Mrp2-deficient Wistar (TR???) rats, Toxicology in Vitro, vol.28, issue.6, pp.1165-1175, 2014. ,
DOI : 10.1016/j.tiv.2014.05.010
Regulation of human hepatic drug transporter expression by pro-inflammatory cytokines, Expert Opinion on Drug Metabolism & Toxicology, vol.29, issue.12, pp.1469-1481, 2009. ,
DOI : 10.1016/S0003-9861(03)00098-5
URL : https://hal.archives-ouvertes.fr/hal-00673340
P-Glycoprotein expression in human, mouse, hamster and rat hepatocytes in primary culture, Carcinogenesis, vol.14, issue.4, pp.781-783, 1993. ,
DOI : 10.1093/carcin/14.4.781
Regulation of biliary drug efflux pump expression by hormones and xenobiotics, Toxicology, vol.167, issue.1, pp.37-46, 2001. ,
DOI : 10.1016/S0300-483X(01)00456-5
The role of hepatic transporters in drug elimination, Expert Opinion on Drug Metabolism & Toxicology, vol.37, issue.4, pp.363-379, 2008. ,
DOI : 10.1080/00498250701570251
Transporters in Drug Development and Clinical Pharmacology, Clinical Pharmacology & Therapeutics, vol.94, issue.1, pp.3-9, 2013. ,
DOI : 10.1038/clpt.2012.44
Membrane transporters in drug development, Nature Reviews Drug Discovery, vol.20, issue.3, pp.215-236, 2010. ,
DOI : 10.1038/nrd3028
Interaction of Digitalis-Like Compounds with Liver Uptake Transporters NTCP, OATP1B1, and OATP1B3, Molecular Pharmaceutics, vol.11, issue.6, pp.1844-1855, 2014. ,
DOI : 10.1021/mp400699p
Effect of cell density and epidermal growth factor on the inducible expression of CYP3A and CYP1A genes in human hepatocytes in primary culture, Hepatology, vol.25, issue.5, pp.1166-1175, 1997. ,
DOI : 10.1002/hep.510250520
Liver cell models in in vitro toxicology, Environmental Health Perspectives, vol.106, issue.Suppl 2, pp.511-532, 1998. ,
DOI : 10.1289/ehp.98106511
P-glycoprotein Expression, Localization, and Function in Sandwich-Cultured Primary Rat and Human Hepatocytes: Relevance to the Hepatobiliary Disposition of a Model Opioid Peptide, Pharmaceutical Research, vol.21, issue.7, pp.1294-1302, 2004. ,
DOI : 10.1023/B:PHAM.0000033018.97745.0d
Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain, AJP: Cell Physiology, vol.292, issue.2, pp.795-806, 2007. ,
DOI : 10.1152/ajpcell.00597.2005
Maintenance of differentiated rat hepatocytes in primary culture., Proceedings of the National Academy of Sciences, vol.82, issue.10, pp.3252-3256, 1985. ,
DOI : 10.1073/pnas.82.10.3252
FUNCTIONAL EXPRESSION OF SINUSOIDAL DRUG TRANSPORTERS IN PRIMARY HUMAN AND RAT HEPATOCYTES, Drug Metabolism and Disposition, vol.33, issue.10, pp.1418-1422, 2005. ,
DOI : 10.1124/dmd.105.004762
Differential Regulation of Sinusoidal and Canalicular Hepatic Drug Transporter Expression by Xenobiotics Activating Drug-Sensing Receptors in Primary Human Hepatocytes, Drug Metabolism and Disposition, vol.34, issue.10, pp.1756-1763, 2006. ,
DOI : 10.1124/dmd.106.010033
URL : https://hal.archives-ouvertes.fr/hal-00699523
Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation, Pharmacological Reviews, vol.62, issue.1, pp.1-96, 2010. ,
DOI : 10.1124/pr.109.002014
Regulation of Hepatic Transporters by Xenobiotic Receptors, Current Drug Metabolism, vol.6, issue.4, pp.309-328, 2005. ,
DOI : 10.2174/1389200054633826
Transporters and Drug-Drug Interactions: Important Determinants of Drug Disposition and Effects, Pharmacological Reviews, vol.65, issue.3, pp.944-966, 2013. ,
DOI : 10.1124/pr.113.007518
Evaluation of Hepatotoxic Potential of Drugs by Inhibition of Bile-Acid Transport in Cultured Primary Human Hepatocytes and Intact Rats, Toxicological Sciences, vol.76, issue.1, pp.220-228, 2003. ,
DOI : 10.1093/toxsci/kfg217
Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes, Drug Metabolism and Disposition, vol.39, issue.9, pp.1503-1510, 2011. ,
DOI : 10.1124/dmd.111.038968
Multidrug resistance protein (MRP) activity in normal mature leukocytes and CD34-positive hematopoietic cells from peripheral blood, Life Sciences, vol.68, issue.11, pp.1323-1331, 2001. ,
DOI : 10.1016/S0024-3205(00)01026-2
Down-Regulation of Organic Anion Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokine Interleukin 1??, Drug Metabolism and Disposition, vol.36, issue.2, pp.217-222, 2008. ,
DOI : 10.1124/dmd.107.016907
URL : https://hal.archives-ouvertes.fr/hal-00673100
Differential Regulation of Drug Transporter Expression by Hepatocyte Growth Factor in Primary Human Hepatocytes, Drug Metabolism and Disposition, vol.37, issue.11, pp.2228-2235, 2009. ,
DOI : 10.1124/dmd.109.028035
URL : https://hal.archives-ouvertes.fr/hal-00673342
Regulation of Drug Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokines Tumor Necrosis Factor-?? or Interleukin-6, Drug Metabolism and Disposition, vol.37, issue.3, pp.685-693, 2009. ,
DOI : 10.1124/dmd.108.023630
URL : https://hal.archives-ouvertes.fr/hal-00673249
Polarized expression of drug transporters in differentiated human hepatoma HepaRG cells, Toxicology in Vitro, vol.27, issue.6, pp.1979-1986, 2013. ,
DOI : 10.1016/j.tiv.2013.07.003
URL : https://hal.archives-ouvertes.fr/hal-00866007
Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration, Am J Physiol, vol.266, pp.1764-1774, 1994. ,
Biliary excretion in primary rat hepatocytes cultured in a collagensandwich configuration, Am J Physiol, vol.277, pp.12-21, 1999. ,
Use of Ca2+ modulation to evaluate biliary excretion in sandwich-cultured rat hepatocytes, J Pharmacol Exp Ther, vol.289, pp.1592-1599, 1999. ,
Influence of isolation procedure, extracellular matrix and dexamethasone on the regulation of membrane transporters gene expression in rat hepatocytes, Biochemical Pharmacology, vol.64, issue.11, pp.1637-1650, 2002. ,
DOI : 10.1016/S0006-2952(02)01382-5
Use of Sandwich-Cultured Hepatocytes To Evaluate Impaired Bile Acid Transport as a Mechanism of Drug-Induced Hepatotoxicity, Molecular Pharmaceutics, vol.4, issue.6, pp.911-918, 2007. ,
DOI : 10.1021/mp0700357
Drug transporter expression in human macrophages, Fundamental & Clinical Pharmacology, vol.76, issue.6, pp.743-752, 2011. ,
DOI : 10.1111/j.1472-8206.2010.00913.x
URL : https://hal.archives-ouvertes.fr/hal-00873191
Expression of cytochrome P-450 enzymes in cultured human hepatocytes, European Journal of Biochemistry, vol.93, issue.2, pp.437-444, 1990. ,
DOI : 10.1016/0009-2797(83)90072-8
Functional expression and regulation of drug transporters in monolayer- and sandwich-cultured mouse hepatocytes, European Journal of Pharmaceutical Sciences, vol.49, issue.1, pp.39-50, 2013. ,
DOI : 10.1016/j.ejps.2013.01.013
URL : https://hal.archives-ouvertes.fr/inserm-00823243
Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation, Cell Differentiation, vol.14, issue.2, pp.135-144, 1984. ,
DOI : 10.1016/0045-6039(84)90038-1
Characterization and inhibition by a wide range of xenobiotics of organic anion excretion by primary human hepatocytes, Biochemical Pharmacology, vol.60, issue.12, pp.1967-1975, 2000. ,
DOI : 10.1016/S0006-2952(00)00496-2
Role of Hepatic Efflux Transporters in Regulating Systemic and Hepatocyte Exposure to Xenobiotics, Annual Review of Pharmacology and Toxicology, vol.54, issue.1, pp.509-535, 2014. ,
DOI : 10.1146/annurev-pharmtox-011613-140021
Drug???Drug Interaction Studies: Regulatory Guidance and An Industry Perspective, The AAPS Journal, vol.15, issue.3, pp.629-645, 2013. ,
DOI : 10.1208/s12248-013-9470-x
Absolute measurement of species differences in sodium taurocholate cotransporting polypeptide (NTCP/Ntcp) and its modulation in cultured hepatocytes, Journal of Pharmaceutical Sciences, vol.102, issue.9, pp.3252-3263, 2013. ,
DOI : 10.1002/jps.23582
tools to study hepatic drug transporters, Drug Metabolism Reviews, vol.30, issue.2, pp.196-217, 2013. ,
DOI : 10.1091/mbc.E11-01-0047
Use of mRNA expression to detect the induction of drug metabolising enzymes in rat and human hepatocytes, Toxicology and Applied Pharmacology, vol.235, issue.1, pp.86-96, 2009. ,
DOI : 10.1016/j.taap.2008.11.019
Absolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human Hepatocytes, Drug Metabolism and Disposition, vol.40, issue.1, pp.93-103, 2012. ,
DOI : 10.1124/dmd.111.042275
Different Dose-Dependent Mechanisms Are Involved in Early Cyclosporine A-Induced Cholestatic Effects in HepaRG Cells, Toxicological Sciences, vol.141, issue.1, pp.244-253, 2014. ,
DOI : 10.1093/toxsci/kfu122
URL : https://hal.archives-ouvertes.fr/hal-01016342
The Role of the Sodium-Taurocholate Cotransporting Polypeptide (NTCP) and of the Bile Salt Export Pump (BSEP) in Physiology and Pathophysiology of Bile Formation, 2011. ,
DOI : 10.1007/978-3-642-14541-4_5
Sandwich-cultured hepatocytes: an in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity, 2010. ,
Effect of Culture Time on the Basal Expression Levels of Drug Transporters in Sandwich-Cultured Primary Rat Hepatocytes, Drug Metabolism and Disposition, vol.39, issue.12, pp.2387-2394, 2011. ,
DOI : 10.1124/dmd.111.039545
Multiparametric High Content Analysis for assessment of neurotoxicity in differentiated neuronal cell lines and human embryonic stem cell-derived neurons, NeuroToxicology, vol.42, pp.33-48, 2014. ,
DOI : 10.1016/j.neuro.2014.03.013