Dissolution kinetic and structural behaviour of natural hydroxyapatite vs. thermal treatment. Comparison to synthetic hydroxyapatite.

F. Z. Mezahi , H. Oudadesse (1) , A. Harabi (2) , A. Lucas-Girot (1) , Y. Le Gal (1) , H. Chaair (3) , G. Cathelineau (1)

1 ISCR - Institut des Sciences Chimiques de Rennes
2 CL-MU - Ceramics Laboratory
3 Laboratoire de génie des Procédés

The dissoln. kinetic and structural behavior of natural hydroxyapatite (N-HA) and synthetic hydroxyapatite (S-HA) was studied vs. sintering temp. and using 'in vitro' expts. Obtained results highlight the chem. stability of N-HA. Any structural modification was obsd. until 1200°C. In the fact S-HA undergoes some modifications. XRD diagrams show the tricalcium phosphate (TCP) phase formation between 800 and 1100°C and tetracalcium phosphate (TetCP) phase formation at 1200°C. The 'in vitro' assay shows that the dissoln. was occurred more in N-HA than in S-HA. The formed TCP activated the dissoln. kinetic and then the pptn. phenomena when a continuous dissoln. of TetCP leaded to slow down the kinetic pptn.

Keywords: hydroxyapatite thermal treatment dissoln pptn bioceramic bone substitute

Domains: Chemical Sciences; Organic chemistry

F. Z. Mezahi, H. Oudadesse, A. Harabi, A. Lucas-Girot, Y. Le Gal, et al.. Dissolution kinetic and structural behaviour of natural hydroxyapatite vs. thermal treatment. Comparison to synthetic hydroxyapatite.. Journal of Thermal Analysis and Calorimetry, 2009, 95, pp.21--29. ⟨10.1007/s10973-008-9065-4⟩. ⟨hal-01151566⟩