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Journal articles
Desulfitative Pd-catalysed coupling reaction using benzenesulfonyl chlorides and enones as the coupling partners.
Abstract : The reaction of benzenesulfonyl chlorides with enones was investigated. β-Ionone and benzalacetone in the presence of a palladium catalyst were found to afford the conjugate addn. products instead of the expected Heck type products. The reaction tolerates a wide variety of substituents on the benzenesulfonyl chloride. It should be noted that no cleavage of the C-Br and C-I bonds was obsd. in the course of the reactions with 4-bromo- or 4-iodobenzenesulfonyl chlorides, allowing further transformations. For example, using 4-bromobenzenesulfonyl chloride as the central unit, consecutive conjugate addn. and subsequent arylation allowed access to substituted bi(hetero)aryls.
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01153408
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, May 19, 2015 - 5:25:07 PM
Last modification on : Thursday, February 11, 2021 - 9:12:12 AM
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, May 19, 2015 - 5:25:07 PM
Last modification on : Thursday, February 11, 2021 - 9:12:12 AM