Quality control in protein synthesis

Reynald Gillet (1)

1 IGDR - Institut de Génétique et Développement de Rennes

Editorial: In all living cells, protein synthesis (also named translation) is a complex and dynamic process mediated by the ribosome. It allows for an accurate correspondence between the genetic information and newly synthesized proteins. While the basics of translation have been known for several decades, the details of how ribosomes perform their task at the molecular level were only recently elucidated, by combining structural and functional studies [1]. In this “golden age” of ribosome studies we have now access not only to a full description of the ribosome itself but also to a detailed sketch of the process at the cellular level, which involves numerous protein and RNA partners that constantly bind and dissociate from the ribosome...

Domaines: Biochimie, Biologie Moléculaire

Reynald Gillet. Quality control in protein synthesis. Biochimie, 2015, 114, pp.1. ⟨10.1016/j.biochi.2015.04.018⟩. ⟨hal-01157678⟩