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Genetic determinants associated with cfxA-positive clinical Capnocytophaga isolates

Abstract : Sir,Capnocytophaga spp. have a role in the pathogenesis of various forms of periodontal disease and systemic infections, particularly severe in neutropenic cancer patients. The prevalence of β-lactam-resistant oral bacteria is increasing in clinical isolates [1]. All of the reported β-lactam-resistant Capnocytophaga isolates are β-lactamase-producers, but minimum inhibitory concentrations (MICs) for the different β-lactams are variable [2]. The objective of the current study was therefore to explain the variability in β-lactam MIC profiles in 31 cfxA gene-positive oral Capnocytophaga spp. clinical isolates with various antibiotypes...
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Submitted on : Thursday, November 19, 2015 - 2:17:46 PM
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Zohreh Tamanai-Shacoori, Anais Dupont, Manon Auffret, Vincent Peton, Frédérique Barloy-Hubler, et al.. Genetic determinants associated with cfxA-positive clinical Capnocytophaga isolates. International Journal of Antimicrobial Agents, Elsevier, 2015, 46 (3), pp.356-358. ⟨10.1016/j.ijantimicag.2015.05.006⟩. ⟨hal-01166301⟩

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