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Proteostasis trumps YAP in colon cancer

Abstract : In this issue of Science Signaling, Zhang et al. find a new role for verteporfin in the control of colorectal cancer progression through the selective induction of proteotoxicity rather than through inhibition of the transcription cofactor YAP. The study further documents the potential strategy of targeting proteostasis to kill cancer cells
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01216201
Contributor : Laurent Jonchère <>
Submitted on : Thursday, October 15, 2015 - 5:06:38 PM
Last modification on : Wednesday, March 27, 2019 - 2:45:06 PM

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Tony Avril, Eric Chevet. Proteostasis trumps YAP in colon cancer. Science Signaling, American Association for the Advancement of Science, 2015, 8 (397), pp.fs18. ⟨10.1126/scisignal.aad3123⟩. ⟨hal-01216201⟩

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