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Journal articles
Synthesis of Symmetrical and Unsymmetrical 1,3-Diheteroarylbenzenes Through Palladium-Catalyzed Direct Arylation of Benzene-1,3-disulfonyl Dichloride and 3-Bromobenzenesulfonyl Chlorides
Abstract : The palladium-catalyzed synthesis of unsymmetrical 1,3-diheteroarylbenzenes was investigated. The first synthetic pathway relies on the desymmetrization of benzene-1,3-disulfonyl dichloride through two successive palladium-catalyzed direct desulfitative arylations with two different heteroarenes. The second strategy employs the orthogonal functionalization of 3-bromobenzenesulfonylchloride using an iterative C–H bond arylation sequence, namely, palladium-catalyzed direct desulfitative arylation followed by a palladium-catalyzed direct arylation step using aryl bromide as the coupling partner. The synthesis of symmetrical 1,3-diheteroarylbenzenes was also investigated
Cited literature [14 references]
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01224511
Contributor : Laurent Jonchère <>
Submitted on : Wednesday, December 2, 2015 - 9:29:25 AM
Last modification on : Friday, July 10, 2020 - 4:05:51 PM
Long-term archiving on: : Friday, April 28, 2017 - 11:36:02 PM
Contributor : Laurent Jonchère <>
Submitted on : Wednesday, December 2, 2015 - 9:29:25 AM
Last modification on : Friday, July 10, 2020 - 4:05:51 PM
Long-term archiving on: : Friday, April 28, 2017 - 11:36:02 PM
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