Skip to Main content Skip to Navigation
Journal articles

Optimising the diagnosis and the treatment of iron overload diseases

Abstract : A number of human disorders are related to chronic iron overload, either of genetic or acquired origin. The multi-organ damage produced by iron excess leads, in adults and in children, to severe clinical consequences, affecting both quality of life and life expectancy. The diagnosis is increasingly based on a non-invasive strategy, resorting to clinical, biological and imaging data. The treatment rests on either venesection or chelation therapy, depending on the etiology. Major advances in the fields of molecular biology, pharmacology, and biotechnology pave the road for key improvements in the diagnostic and therapeutic management of the patients.
Complete list of metadatas

Cited literature [51 references]  Display  Hide  Download

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01231411
Contributor : Laurent Jonchère <>
Submitted on : Thursday, April 28, 2016 - 3:37:43 PM
Last modification on : Tuesday, December 11, 2018 - 10:54:02 AM

File

Optimising the diagnosis and t...
Files produced by the author(s)

Identifiers

Citation

Pierre Brissot. Optimising the diagnosis and the treatment of iron overload diseases. Expert Review of Gastroenterology & Hepatology, Future Drugs, 2007-, 2016, 10 (3), pp.359-370. ⟨10.1586/17474124.2016.1119043⟩. ⟨hal-01231411⟩

Share

Metrics

Record views

859

Files downloads

785