Skip to Main content Skip to Navigation
Journal articles

Recent advances in cancer treatment by Iron Chelators

Abstract : The development of new therapeutic alternatives for cancers is a major public health priority. Among the more promising approaches, the iron depletion strategy based on metal chelation in the tumoral environment has been particularly studied in recent decades. After a short description of the importance of iron for cancer cell proliferation, we will review the different iron chelators developed as potential chemotherapeutics. Finally, the recent efforts to vectorize the chelating agents specifically in the microtumoral environment will be discussed in detail
Document type :
Journal articles
Complete list of metadatas

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01237081
Contributor : Laurent Jonchère <>
Submitted on : Wednesday, January 6, 2016 - 11:30:12 AM
Last modification on : Monday, March 25, 2019 - 4:04:02 PM
Long-term archiving on: : Thursday, April 7, 2016 - 3:56:02 PM

File

Recent advances in cancer trea...
Files produced by the author(s)

Identifiers

Citation

Vincent Corcé, Sébastien G. Gouin, Stéphanie Renaud, François Gaboriau, David Deniaud. Recent advances in cancer treatment by Iron Chelators. Bioorganic and Medicinal Chemistry Letters, Elsevier, 2016, 26 (2), pp.251-256. ⟨10.1016/j.bmcl.2015.11.094⟩. ⟨hal-01237081⟩

Share

Metrics

Record views

450

Files downloads

641