Synthesis of Fluorine-Containing Exoalkylidene β-Lactams

Assaad Nasr El Dine; Danielle Grée; Thierry Roisnel; Elsa Caytan; Ali Hachem; René Grée

doi:10.1002/ejoc.201501347

Journal articles

Synthesis of Fluorine-Containing Exoalkylidene β-Lactams

Assaad Nasr El Dine ¹ Danielle Grée ² Thierry Roisnel ² Elsa Caytan ² Ali Hachem ¹ René Grée ²

1 LU - Lebanese University [Beirut]

2 ISCR - Institut des Sciences Chimiques de Rennes

Abstract : The Kinugasa reaction, applied to propargylic gem-difluorides, allows a very direct and efficient synthesis of new exoalkylidene β-lactams with a fluorine in the vinylic position

Keywords : Lactams Fluorine Alkynes Nitrones Small ring systems

Document type :

Journal articles

Domain :

Chemical Sciences

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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01242905
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Submitted on : Monday, December 14, 2015 - 12:08:39 PM
Last modification on : Wednesday, April 7, 2021 - 3:18:08 PM

Synthesis of Fluorine-Containing Exoalkylidene β-Lactams

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Synthesis of Fluorine-Containing Exoalkylidene β-Lactams

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