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Synthesis of Fluorine-Containing Exoalkylidene β-Lactams

Assaad Nasr El Dine 1 Danielle Grée 2 Thierry Roisnel 2 Elsa Caytan 2 Ali Hachem 1 René Grée 2
1 LU - Lebanese University [Beirut]
2 ISCR - Institut des Sciences Chimiques de Rennes
Abstract : The Kinugasa reaction, applied to propargylic gem-difluorides, allows a very direct and efficient synthesis of new exoalkylidene β-lactams with a fluorine in the vinylic position
Keywords : Lactams Fluorine Alkynes Nitrones Small ring systems
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01242905
Contributor : Laurent Jonchère Connect in order to contact the contributor
Submitted on : Monday, December 14, 2015 - 12:08:39 PM
Last modification on : Wednesday, April 7, 2021 - 3:18:08 PM

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Assaad Nasr El Dine, Danielle Grée, Thierry Roisnel, Elsa Caytan, Ali Hachem, et al.. Synthesis of Fluorine-Containing Exoalkylidene β-Lactams. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2016, 2016 (3), pp.556-561. ⟨10.1002/ejoc.201501347⟩. ⟨hal-01242905⟩

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