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Journal articles
Copper-catalyzed asymmetric conjugate addition of organometallic reagents to extended Michael acceptors
Abstract : The copper-catalyzed asymmetric conjugate addition (ACA) of nucleophiles onto polyenic Michael acceptors represents an attractive and powerful methodology for the synthesis of relevant chiral molecules, as it enables in a straightforward manner the sequential generation of two or more stereogenic centers. In the last decade, various chiral copper-based catalysts were evaluated in combination with different nucleophiles and Michael acceptors, and have unambiguously demonstrated their usefulness in the control of the regio- and enantioselectivity of the addition. The aim of this review is to report recent breakthroughs achieved in this challenging field
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01254825
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, January 12, 2016 - 4:47:51 PM
Last modification on : Friday, July 10, 2020 - 4:01:04 PM
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, January 12, 2016 - 4:47:51 PM
Last modification on : Friday, July 10, 2020 - 4:01:04 PM
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