Skip to Main content Skip to Navigation
Journal articles

Validation of a New Classification Method of Postoperative Complications in Patients Undergoing Coronary Surgery

Abstract : Objective The authors aimed to validate the European Multicenter Study on Coronary Artery Bypass Grafting (E-CABG) classification of postoperative complications in patients undergoing coronary artery bypass grafting (CABG). Design Retrospective, observational study. Setting University hospital. Participants A total of 2,764 patients with severe coronary artery disease. Complete baseline, operative, and postoperative data were available for patients who underwent isolated CABG. Interventions Isolated CABG. Measurements and Main Results The E-CABG complication classification was used to stratify the severity and prognostic impact of adverse postoperative events. Primary outcome endpoints were 30-day, 90-day, and long-term all-cause mortality. The secondary outcome endpoints was the length of intensive care unit stay. Both the E-CABG complication grades and additive score were predictive of 30-day (area under the receiver operating characteristics curve 0.866, 95% confidence interval [CI] 0.829-0.903; and 0.876; 95% CI 0.844-0.908, respectively) and 90-day (area under the receiver operating characteristics curve 0.850, 95% CI 0.812-0.887; and 0.863, 95% CI 0.829-0.897, respectively) all-cause mortality. The complication grades were independent predictors of increased mortality at actuarial (log-rank: p<0.0001) and adjusted analysis (p<0.0001; grade 1: hazard ratio [HR] 1.757, 95% CI 1.111-2.778; grade 2: HR 2.704, 95% CI 1.664-4.394; grade 3: HR 5.081, 95% CI 3.148-8.201). When patients who died within 30 days were excluded from the analysis, this grading method still was associated with late mortality (p<0.0001). The grading method (p<0.0001) and the additive score (rho, 0.514; p<0.0001) were predictive of the length of intensive care unit stay. Conclusions The E-CABG postoperative complication classification seems to be a promising tool for stratifying the severity and prognostic impact of postoperative complications in patients undergoing cardiac surgery
Document type :
Journal articles
Complete list of metadatas

Cited literature [9 references]  Display  Hide  Download

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01259442
Contributor : Laurent Jonchère <>
Submitted on : Wednesday, January 27, 2016 - 12:27:02 PM
Last modification on : Thursday, July 4, 2019 - 7:09:40 AM
Long-term archiving on: : Thursday, April 28, 2016 - 11:18:59 AM

File

Validation of a New Classifica...
Files produced by the author(s)

Identifiers

Collections

Citation

Eeva-Maija Kinnunen, Matti-Aleksi Mosorin, Andrea Perrotti, Vito G. Ruggieri, Peter Svenarud, et al.. Validation of a New Classification Method of Postoperative Complications in Patients Undergoing Coronary Surgery. Journal of Cardiothoracic and Vascular Anesthesia, WB Saunders, 2015, In press. ⟨10.1053/j.jvca.2015.09.019⟩. ⟨hal-01259442⟩

Share

Metrics

Record views

212

Files downloads

173