Nitride coating enhances endothelialization on biomedical NiTi shape memory alloy

Raluca Ion (1) , Catalin Luculescu (2) , Anisoara Cimpean (1) , Philippe Marx (3) , Doina-Margareta Gordin (4) , Thierry Gloriant (4)

1 Department of Biochemistry and Molecular Biology
2 INFLPR - National Institute for Lasers, Plasma, and Radiation Physics [Magurele-Ilfov]
3 AMF - Société Alliages à Mémoire de Forme
4 ISCR - Institut des Sciences Chimiques de Rennes

Surface nitriding was demonstrated to be an effective process for improving the biocompatibility of implantable devices. In this study, we investigated the benefits of nitriding the NiTi shape memory alloy for vascular stent applications. Results from cell experiments indicated that, compared to untreated NiTi, a superficial gas nitriding treatment enhanced the adhesion of human umbilical vein endothelial cells (HUVECs), cell spreading and proliferation. This investigation provides data to demonstrate the possibility of improving the rate of endothelialization on NiTi by means of nitride coating.

Keywords: NiTi alloy; surface nitriding; HUVEC; endothelialization

Domains: Chemical Sciences; Life Sciences [q-bio]

Raluca Ion, Catalin Luculescu, Anisoara Cimpean, Philippe Marx, Doina-Margareta Gordin, et al.. Nitride coating enhances endothelialization on biomedical NiTi shape memory alloy. Materials Science and Engineering: C, 2016, 62, pp.686-691. ⟨10.1016/j.msec.2016.02.031⟩. ⟨hal-01272661⟩