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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Pierre-Emmanuel Noly 1 Julien Guihaire 2, 1 Matthieu Coblence 1 Peter Dorfmüller 3, 4, 1 Elie Fadel 1 Olaf Mercier 1
1 CCML - Centre Chirurgical Marie Lannelongue
2 Service de chirurgie thoracique cardiaque et vasculaire [Rennes]
3 DHU TORINO - Service de Pneumologie et Réanimation Respiratoire
4 UP11 - Université Paris-Sud - Paris 11
Abstract : Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Right Ventricular (RV) dysfunction were induced in piglets by progressive obstruction of the pulmonary arteries. Consequences were remarkably similar to those observed in CTEPH patients. This animal model would be a very useful tool for pathophysiology and therapeutic experiments on CTEPH and RV failure
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Journal articles
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01275478
Contributor : Nelly Brenner <>
Submitted on : Wednesday, February 17, 2016 - 3:03:47 PM
Last modification on : Wednesday, September 16, 2020 - 5:10:43 PM

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UNIV-RENNES1 | UNIV-PARIS-SACLAY | UNIV-RENNES

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Pierre-Emmanuel Noly, Julien Guihaire, Matthieu Coblence, Peter Dorfmüller, Elie Fadel, et al.. Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet. Journal of visualized experiments : JoVE, JoVE, 2015, ⟨10.3791/53133⟩. ⟨hal-01275478⟩

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