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Minor Pyranonaphthoquinones from the Apothecia of the Lichen Ophioparma ventosa

Abstract : Four new quinonoid naphthopyranones, ophioparmin (1), 4-methoxyhaemoventosins (2a and 2b), and 4-hydroxyhaemoventosin (3), together with anhydrofusarubin lactone (4) and haemoventosin (5) were isolated from the fruiting bodies of Ophioparma ventosa, a crustose lichen. Their structures were determined by spectroscopic analyses, and the absolute configurations of 1 and 2 were elucidated through experimental and calculated electronic circular dichroism analyses. Compounds 1, 2, and 5 exhibited moderate to strong antioxidant activities. The main pigment haemoventosin exhibited significant cytotoxicity toward a panel of nine cell lines
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01286283
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Submitted on : Thursday, March 10, 2016 - 3:37:06 PM
Last modification on : Monday, May 18, 2020 - 2:38:22 PM

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Pierre Le Pogam, Anne-Cécile Le Lamer, Bandi Siva, Béatrice Legouin, Arnaud Bondon, et al.. Minor Pyranonaphthoquinones from the Apothecia of the Lichen Ophioparma ventosa. Journal of Natural Products, American Chemical Society, 2016, 79 (4), pp.1005-1011. ⟨10.1021/acs.jnatprod.5b01073⟩. ⟨hal-01286283⟩

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