Skip to Main content Skip to Navigation
Journal articles

New organometallic Schiff-base copper complexes as efficient "click" reaction precatalysts

Abstract : A new ferrocenyl-contg. unsym. CuII-Schiff-base complex, 2, and its covalently poly(methyl)(methacrylate) (PMMA)-grafted counterpart 3 were synthesized and characterized using elemental anal., electrospray ionization (ESI) mass spectrometry for 2, and FT-IR spectroscopy. New complex 3 was employed as a precatalyst in the copper-catalyzed [3+2] cycloaddn. of org. azides to alkynes (CuAAC, "click" reaction). The active CuI species generated from only 0.2 mol% of CuII precatalyst 2 and sodium ascorbate displayed high activity at room temp. in ethanol for 24 h allowing the synthesis of a wide variety of 1,4-disubstituted 1,2,3-triazoles in high isolated yields. The PMMA-supported catalyst 3 is also efficient and has been reused at least three times in these "click" reactions without any loss of activity or copper leaching.
Document type :
Journal articles
Complete list of metadatas

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01295502
Contributor : Laurent Jonchère <>
Submitted on : Thursday, March 31, 2016 - 11:13:22 AM
Last modification on : Thursday, March 5, 2020 - 2:04:46 PM

Identifiers

Citation

Xiang Liu, Néstor Novoa, Carolina Manzur, David Carrillo, Jean-René Hamon. New organometallic Schiff-base copper complexes as efficient "click" reaction precatalysts. New Journal of Chemistry, Royal Society of Chemistry, 2016, 40 (4), pp.3308-3313. ⟨10.1039/C5NJ02681D⟩. ⟨hal-01295502⟩

Share

Metrics

Record views

181