Tandem C(sp2)-OMe Activation/C(sp2)-C(sp2) Coupling in Early Transition-Metal Complexes: Aromatic C-O Activation beyond Late Transition Metals

Vasily Radkov (1) , Thierry Roisnel (2) , Alexander Trifonov (1) , Jean-François Carpentier (2) , Evgueni Kirillov (2)

1 Russian Acad Sci, GA Razunaev Inst Organomet Chem
2 ISCR - Institut des Sciences Chimiques de Rennes

We report on combined structural, kinetic, and computational studies unraveling the mechanism of a unique, highly selective intramolecular C(sp(2))-OMe cleavage/C(sp(2))-C(sp(2)) coupling tandem reaction in group 3 metal (Y and Sc) complexes of amidine-amidopyridinate ligands. The latter process represents a rare stoichiometric model of the nonredox cleavage of inert C(sp(2))-O bonds relevant to cross-coupling reactions of aromatic ethers catalyzed by late transition metals.

Domains: Chemical Sciences

Vasily Radkov, Thierry Roisnel, Alexander Trifonov, Jean-François Carpentier, Evgueni Kirillov. Tandem C(sp2)-OMe Activation/C(sp2)-C(sp2) Coupling in Early Transition-Metal Complexes: Aromatic C-O Activation beyond Late Transition Metals. Journal of the American Chemical Society, 2016, 138 (13), pp.4350-4353. ⟨10.1021/jacs.6b01877⟩. ⟨hal-01295507⟩