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A new direct synthesis of α-methylene- and α-alkylidene-β-lactams

Abstract : The Kinugasa reaction applied to alkynes bearing a nucleofuge in propargylic position affords directly, and in fair yields, α-methylene- or α-alkylidene- β-lactams
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Submitted on : Thursday, June 2, 2016 - 10:23:00 AM
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Marwa Hussein, Assaad Nasr El Dine, Fares Fares, Vincent Dorcet, Ali Hachem, et al.. A new direct synthesis of α-methylene- and α-alkylidene-β-lactams. Tetrahedron Letters, Elsevier, 2016, 57 (18), pp.1990-1993. ⟨10.1016/j.tetlet.2016.03.083⟩. ⟨hal-01295513⟩



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