D. Acosta-alvear, Y. Zhou, A. Blais, M. Tsikitis, N. H. Lents et al., XBP1 Controls Diverse Cell Type- and Condition-Specific Transcriptional Regulatory Networks, Molecular Cell, vol.27, issue.1, pp.53-66, 2007.
DOI : 10.1016/j.molcel.2007.06.011

L. Ait-ghezali, A. Arbabian, A. Jeibmann, M. Hasselblatt, G. G. Hallaert et al., Loss of endoplasmic reticulum calcium pump expression in choroid plexus tumours, Neuropathology and Applied Neurobiology, vol.37, issue.Pt 1, pp.726-735, 2014.
DOI : 10.1111/nan.12098

F. Y. Al-rawashdeh, P. Scriven, I. C. Cameron, P. V. Vergani, and L. Wyld, Unfolded protein response activation contributes to chemoresistance in hepatocellular carcinoma, European Journal of Gastroenterology & Hepatology, vol.22, issue.9, pp.1099-105, 2010.
DOI : 10.1097/MEG.0b013e3283378405

N. Andruska, X. Zheng, X. Yang, W. G. Helferich, and D. J. Shapiro, Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor ??-positive breast cancer, Oncogene, vol.62, issue.29, pp.3760-3769, 2015.
DOI : 10.1371/journal.pbio.0020108

D. Anguilar, J. M. Martín, J. Aneiros, V. Arjona, J. L. Lara et al., The fine structure of choroid plexus carcinoma, Histopathology, vol.91, issue.6, pp.939-946, 1983.
DOI : 10.1016/S0022-5320(80)90027-1

G. Auf, A. Jabouille, S. Guerit, R. Pineau, M. Delugin et al., Inositol-requiring enzyme 1?? is a key regulator of angiogenesis and invasion in malignant glioma, Proceedings of the National Academy of Sciences, vol.107, issue.35, pp.15553-15561, 2010.
DOI : 10.1073/pnas.0914072107

G. Auf, A. Jabouille, S. Guérit, R. Pineau, M. Delugin et al., Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma, Proceedings of the National Academy of Sciences of the United States of America, pp.15553-15558, 2010.

G. Auf, A. Jabouille, M. Delugin, S. Guérit, R. Pineau et al., High epiregulin expression in human U87 glioma cells relies on IRE1?? and promotes autocrine growth through EGF receptor, BMC Cancer, vol.52, issue.3, p.597, 2013.
DOI : 10.1002/glia.20236
URL : https://hal.archives-ouvertes.fr/inserm-00922900

W. E. Balch, R. I. Morimoto, A. Dillin, and J. W. Kelly, Adapting Proteostasis for Disease Intervention, Science, vol.319, issue.5865, pp.916-925, 2008.
DOI : 10.1126/science.1141448

A. Bertolotti, Y. Zhang, L. M. Hendershot, H. P. Harding, and D. Ron, Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response, Nat Cell Biol, vol.2, pp.326-358, 2000.

M. Bi, C. Naczki, M. Koritzinsky, D. Fels, J. Blais et al., ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth, The EMBO Journal, vol.162, issue.19, pp.3470-81, 2005.
DOI : 10.1038/sj.emboj.7600777

M. J. Bissell and W. C. Hines, Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression, Nature Medicine, vol.23, issue.3, pp.320-329, 2011.
DOI : 10.1038/nm.2328

J. D. Blais, V. Filipenko, M. Bi, H. P. Harding, D. Ron et al., Activating Transcription Factor 4 Is Translationally Regulated by Hypoxic Stress, Molecular and Cellular Biology, vol.24, issue.17, pp.7469-82, 2004.
DOI : 10.1128/MCB.24.17.7469-7482.2004

J. D. Blais, C. L. Addison, R. Edge, T. Falls, H. Zhao et al., Perk-Dependent Translational Regulation Promotes Tumor Cell Adaptation and Angiogenesis in Response to Hypoxic Stress, Molecular and Cellular Biology, vol.26, issue.24, pp.9517-9549, 2006.
DOI : 10.1128/MCB.01145-06

M. Bouchecareilh, A. Higa, S. Fribourg, M. Moenner, and E. Chevet, Peptides derived from the bifunctional kinase/RNase enzyme IRE1?? modulate IRE1?? activity and protect cells from endoplasmic reticulum stress, The FASEB Journal, vol.25, issue.9, pp.3115-3144, 2011.
DOI : 10.1096/fj.11-182931

M. Calfon, H. Zeng, F. Urano, J. H. Till, S. R. Hubbard et al., IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA, Nature, vol.415, issue.6867, pp.92-98, 2002.
DOI : 10.1038/415092a

X. Chen, D. Iliopoulos, Q. Zhang, Q. Tang, M. B. Greenblatt et al., XBP1 promotes triple-negative breast cancer by controlling the HIF1?? pathway, Nature, vol.365, issue.7494, pp.103-110, 2014.
DOI : 10.1038/nature13119

E. Chevet, C. Hetz, and A. Samali, Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis, Cancer Discovery, vol.5, issue.6, pp.586-597, 2015.
DOI : 10.1158/2159-8290.CD-14-1490
URL : https://hal.archives-ouvertes.fr/hal-01152845

J. W. Choi, M. A. Schroeder, J. N. Sarkaria, and R. J. Bram, Cyclophilin B supports Myc and mutant p53-dependent survival of glioblastoma multiforme cells. Cancer Research, pp.484-496, 2014.

P. J. Cimino, Malignant progression to anaplastic meningioma: Neuropathology, molecular pathology, and experimental models, Experimental and Molecular Pathology, vol.99, issue.2, pp.354-359, 2015.
DOI : 10.1016/j.yexmp.2015.08.007

G. Cossu, M. Levivier, R. T. Daniel, and M. Messerer, The Role of Mifepristone in Meningiomas Management: A Systematic Review of the Literature, BioMed Research International, vol.10, issue.18, 2015.
DOI : 10.1093/annonc/mdq634

M. E. Couce, F. V. Aker, and B. W. Scheithauer, Chordoid Meningioma, The American Journal of Surgical Pathology, vol.24, issue.7, pp.899-905, 2000.
DOI : 10.1097/00000478-200007000-00001

D. Y. Dadey, V. Kapoor, A. Khudanyan, F. Urano, A. H. Kim et al., The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma, Oncotarget, 2015.

D. Girolami, U. Fèvre-montange, M. Seilhean, D. Jouvet, and A. , Pathology of tumors of the pineal region, Revue Neurologique, vol.164, issue.11, pp.882-895, 2008.
DOI : 10.1016/j.neurol.2008.01.008

N. Dejeans, O. Pluquet, S. Lhomond, F. Grise, M. Bouchecareilh et al., Autocrine control of glioma cells adhesion and migration through IRE1??-mediated cleavage of SPARC mRNA, Journal of Cell Science, vol.125, issue.18, pp.4278-87, 2012.
DOI : 10.1242/jcs.099291

N. Dejeans, S. Manie, C. Hetz, F. Bard, T. Hupp et al., Addicted to secrete ??? novel concepts and targets in cancer therapy, Trends in Molecular Medicine, vol.20, issue.5, pp.242-50, 2014.
DOI : 10.1016/j.molmed.2013.12.003

N. Dejeans, K. Barroso, M. E. Fernandez-zapico, A. Samali, and E. Chevet, Novel roles of the unfolded protein response in the control of tumor development and aggressiveness, Seminars in Cancer Biology, vol.33, pp.67-73, 2015.
DOI : 10.1016/j.semcancer.2015.04.007
URL : https://hal.archives-ouvertes.fr/hal-01150385

D. Vecchio, C. A. Feng, Y. Sokol, E. S. Tillman, E. J. Sanduja et al., De-Differentiation Confers Multidrug Resistance Via Noncanonical PERK-Nrf2 Signaling, PLoS Biology, vol.5, issue.9, 2014.
DOI : 10.1371/journal.pbio.1001945.s006

M. S. Denzel, N. J. Storm, A. Gutschmidt, R. Baddi, Y. Hinze et al., Hexosamine Pathway Metabolites Enhance Protein Quality Control and Prolong Life, Cell, vol.156, issue.6, pp.1167-78, 2014.
DOI : 10.1016/j.cell.2014.01.061

N. Dioufa, E. Kassi, A. G. Papavassiliou, and H. Kiaris, Atypical induction of the unfolded protein response by mifepristone, Endocrine, vol.279, issue.10, pp.167-73, 2010.
DOI : 10.1007/s12020-010-9362-0

W. Dong, Y. Zhang, M. Yan, H. Liu, Z. Chen et al., Upregulation of 78???kDa glucose???regulated protein in macrophages in peripheral joints of active ankylosing spondylitis, Scandinavian Journal of Rheumatology, vol.8, issue.2, pp.427-461, 2008.
DOI : 10.2174/156652406775574523

B. Drogat, P. Auguste, D. T. Nguyen, M. Bouchecareilh, R. Pineau et al., IRE1 Signaling Is Essential for Ischemia-Induced Vascular Endothelial Growth Factor-A Expression and Contributes to Angiogenesis and Tumor Growth In vivo, Cancer Research, vol.67, issue.14, pp.6700-6707, 2007.
DOI : 10.1158/0008-5472.CAN-06-3235

C. G. Eberhart, T. Tihan, and P. C. Burger, Nuclear Localization and Mutation of ??-Catenin in Medulloblastomas, Journal of Neuropathology & Experimental Neurology, vol.59, issue.4, pp.333-337, 2000.
DOI : 10.1093/jnen/59.4.333

L. M. Epple, R. D. Dodd, A. L. Merz, A. M. Dechkovskaia, M. Herring et al., Induction of the Unfolded Protein Response Drives Enhanced Metabolism and Chemoresistance in Glioma Cells, PLoS ONE, vol.279, issue.8, p.73267, 2013.
DOI : 10.1371/journal.pone.0073267.s006

D. R. Fels and C. Koumenis, The PERK/eIF2??/ATF4 module of the UPR in hypoxia resistance and tumor growth, Cancer Biology & Therapy, vol.5, issue.7, pp.723-731, 2006.
DOI : 10.4161/cbt.5.7.2967

Y. X. Feng, E. S. Sokol, D. Vecchio, C. A. Sanduja, S. Claessen et al., Epithelial-to-Mesenchymal Transition Activates PERK-eIF2?? and Sensitizes Cells to Endoplasmic Reticulum Stress, Cancer Discovery, vol.4, issue.6, pp.702-717, 2014.
DOI : 10.1158/2159-8290.CD-13-0945

A. Fernández, R. Ordóñez, R. J. Reiter, J. González-gallego, and J. L. Mauriz, Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis, Journal of Pineal Research, vol.55, issue.3, pp.292-307, 2015.
DOI : 10.1111/jpi.12264

P. M. Fernandez, S. O. Tabbara, L. K. Jacobs, F. C. Manning, T. N. Tsangaris et al., Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions, Breast Cancer Research and Treatment, vol.58, issue.Suppl.740, pp.15-26, 2000.
DOI : 10.1023/A:1006332011207

C. M. Ferrer, T. P. Lynch, V. L. Sodi, J. N. Falcone, L. P. Schwab et al., O-GlcNAcylation Regulates Cancer Metabolism and Survival Stress Signaling via Regulation of the HIF-1 Pathway, Molecular Cell, vol.54, issue.5, pp.820-851, 2014.
DOI : 10.1016/j.molcel.2014.04.026

M. Fevre-montange, J. Champier, A. Szathmari, C. Brisson, A. Reboul et al., Histological features and expression of enzymes implicated in melatonin synthesis in pineal parenchymal tumours and in cultured tumoural pineal cells, Neuropathology and Applied Neurobiology, vol.63, issue.3, pp.296-305, 2008.
DOI : 10.1016/S0090-3019(98)00028-7

M. Firczuk, M. Gabrysiak, J. Barankiewicz, A. Domagala, D. Nowis et al., GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy, Cell Death and Disease, vol.9, issue.7, p.741, 2013.
DOI : 10.1158/0008-5472.CAN-05-1242

W. Fu, X. Wu, J. Li, Z. Mo, Z. Yang et al., Upregulation of GRP78 in Renal Cell Carcinoma and Its Significance, Urology, vol.75, issue.3, pp.603-610, 2010.
DOI : 10.1016/j.urology.2009.05.007

T. Fujimoto, K. Yoshimatsu, K. Watanabe, H. Yokomizo, T. Otani et al., Overexpression of human X-box binding protein 1 (XBP-1) in colorectal adenomas and adenocarcinomas, Anticancer Res, vol.27, pp.127-158, 2007.

R. Ghosh, L. Wang, E. S. Wang, B. G. Perera, A. Igbaria et al., Allosteric Inhibition of the IRE1?? RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress, Cell, vol.158, issue.3, pp.534-582
DOI : 10.1016/j.cell.2014.07.002

H. A. Hamed, A. Yacoub, M. A. Park, P. Eulitt, D. Sarkar et al., OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins, Cancer Biology & Therapy, vol.9, issue.7, pp.526-562, 2010.
DOI : 10.4161/cbt.9.7.11116

D. Han, A. G. Lerner, L. Vande-walle, J. Upton, W. Xu et al., IRE1?? Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates, Cell, vol.138, issue.3, pp.562-75, 2009.
DOI : 10.1016/j.cell.2009.07.017

J. Han, S. H. Back, J. Hur, Y. H. Lin, R. Gildersleeve et al., ER-stress-induced transcriptional regulation increases protein synthesis leading to cell??death, Nature Cell Biology, vol.93, issue.5, pp.481-90, 2013.
DOI : 10.1006/dbio.2000.9699

D. Hanahan and R. A. Weinberg, Hallmarks of Cancer: The Next Generation, Cell, vol.144, issue.5, pp.646-674, 2011.
DOI : 10.1016/j.cell.2011.02.013

H. P. Harding, Y. Zhang, and D. Ron, Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase, Nature, vol.397, pp.271-275, 1999.

L. S. Hart, J. T. Cunningham, T. Datta, S. Dey, F. Tameire et al., ER stress???mediated autophagy promotes Myc-dependent transformation and tumor growth, Journal of Clinical Investigation, vol.122, issue.12, pp.4621-4655
DOI : 10.1172/JCI62973DS1

C. Harz, N. Ludwig, S. Lang, T. V. Werner, V. Galata et al., Secretion and Immunogenicity of the Meningioma-Associated Antigen TXNDC16, The Journal of Immunology, vol.193, issue.6, pp.3146-3154, 1950.
DOI : 10.4049/jimmunol.1303098

S. Hasan, M. Young, T. Albert, A. H. Shah, C. Okoye et al., The Role of Adjuvant Radiotherapy After Gross Total Resection of Atypical Meningiomas, World Neurosurgery, vol.83, issue.5, pp.808-815, 2015.
DOI : 10.1016/j.wneu.2014.12.037

K. Haze, H. Yoshida, H. Yanagi, T. Yura, and K. Mori, Mammalian Transcription Factor ATF6 Is Synthesized as a Transmembrane Protein and Activated by Proteolysis in Response to Endoplasmic Reticulum Stress, Molecular Biology of the Cell, vol.10, issue.11, pp.3787-99, 1999.
DOI : 10.1091/mbc.10.11.3787

C. Hetz, P. Thielen, S. Matus, M. Nassif, F. Court et al., XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy, Genes & Development, vol.23, issue.19, pp.2294-306, 2009.
DOI : 10.1101/gad.1830709

C. Hetz, F. Martinon, D. Rodriguez, and L. H. Glimcher, The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1??, Physiological Reviews, vol.91, issue.4, pp.1219-1262, 2011.
DOI : 10.1152/physrev.00001.2011

C. Hetz, E. Chevet, and H. P. Harding, Targeting the unfolded protein response in disease, Nature Reviews Drug Discovery, vol.11, issue.9, pp.703-722, 2013.
DOI : 10.1038/nrd3976

C. Hetz, E. Chevet, and S. A. Oakes, Proteostasis control by the unfolded protein response, Nature Cell Biology, vol.276, issue.7, pp.829-867, 2015.
DOI : 10.1038/nrd3976
URL : https://hal.archives-ouvertes.fr/hal-01175531

A. Higa, S. Taouji, S. Lhomond, D. Jensen, M. E. Fernandez-zapico et al., Endoplasmic Reticulum Stress-Activated Transcription Factor ATF6?? Requires the Disulfide Isomerase PDIA5 To Modulate Chemoresistance, Molecular and Cellular Biology, vol.34, issue.10, pp.1839-1888, 2014.
DOI : 10.1128/MCB.01484-13

D. C. Hiss and G. A. Gabriels, Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part II: targeting cell cycle events, caspases, NF-??B and the proteasome, Expert Opinion on Drug Discovery, vol.85, issue.9, pp.907-928, 2009.
DOI : 10.1007/s10495-006-9006-2

K. L. Ho, Ultrastructure of cerebellar capillary hemangioblastoma, Acta Neuropathologica, vol.44, issue.Suppl, pp.345-353, 1987.
DOI : 10.1007/BF00687211

K. L. Ho, Microtubular aggregates within rough endoplasmic reticulum in myxopapillary ependymoma of the filum terminale, Archives of Pathology & Laboratory Medicine, vol.114, pp.956-960, 1990.

H. Larsen, A. Frandsen, A. Treiman, and M. , Upregulation of the SERCA-type Ca2+ pump activity in response to endoplasmic reticulum stress in PC12 cells, BMC Biochemistry, vol.2, issue.1, p.4, 2001.
DOI : 10.1186/1471-2091-2-4

J. Hollien and J. S. Weissman, Decay of Endoplasmic Reticulum-Localized mRNAs During the Unfolded Protein Response, Science, vol.313, issue.5783, pp.104-111, 2006.
DOI : 10.1126/science.1129631

J. Hollien, J. H. Lin, H. Li, N. Stevens, P. Walter et al., Regulated Ire1-dependent decay of messenger RNAs in mammalian cells, The Journal of Cell Biology, vol.186, issue.3, pp.323-354, 2009.
DOI : 10.1128/MCB.22.11.3864-3874.2002

X. Hou, Y. Liu, H. Liu, X. Chen, M. Liu et al., PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2's mitochondria translocation, Scientific Reports, vol.21, p.9065, 2015.
DOI : 10.1038/srep09065

I. Gómez, J. C. , M. Orgueira, and A. , An integrative analysis of meningioma tumors reveals the determinant genes and pathways of malignant transformation, Frontiers in Oncology, vol.4, p.147, 2014.

T. Iwawaki, A. Hosoda, T. Okuda, Y. Kamigori, C. Nomura-furuwatari et al., Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress, Nature Cell Biology, vol.3, issue.2, pp.158-64, 2001.
DOI : 10.1038/35055065

A. Jabouille, M. Delugin, R. Pineau, A. Dubrac, F. Soulet et al., Glioblastoma invasion and cooption depend on IRE1?? endoribonuclease activity, Glioblastoma invasion and cooption depend on IRE1? endoribonuclease activity, pp.24922-24934, 2015.
DOI : 10.18632/oncotarget.4679
URL : https://hal.archives-ouvertes.fr/hal-01197351

S. Jamison, Y. Lin, and W. Lin, Pancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor A. PloS One, p.120252, 2015.

C. Verschraegen, Double-Blind Phase III Randomized Trial of the Antiprogestin Agent Mifepristone in the Treatment of Unresectable Meningioma: SWOG S9005, Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, vol.33, pp.4093-4098, 2015.

G. G. Johnson, M. C. White, J. Wu, M. Vallejo, and M. Grimaldi, The deadly connection between endoplasmic reticulum, Ca2+, protein synthesis, and the endoplasmic reticulum stress response in malignant glioma cells, Neuro-Oncology, vol.16, issue.8, pp.1086-1099, 2014.
DOI : 10.1093/neuonc/nou012

A. Jouvet, F. Fauchon, P. Liberski, G. Saint-pierre, M. Didier-bazes et al., Papillary Tumor of the Pineal Region, The American Journal of Surgical Pathology, vol.27, issue.4, pp.505-512, 2003.
DOI : 10.1097/00000478-200304000-00011

J. Jurkin, T. Henkel, A. F. Nielsen, M. Minnich, J. Popow et al., The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells, EMBO J, 2014.

K. T. Kline, I. Damjanov, S. M. Katz, and H. Schmidek, Pineoblastoma: An electron microscopic study, Cancer, vol.35, issue.5, pp.1692-1699, 1979.
DOI : 10.1002/1097-0142(197911)44:5<1692::AID-CNCR2820440524>3.0.CO;2-K

L. Mercier, M. Lefranc, F. Mijatovic, T. Debeir, O. Haibe-kains et al., Evidence of galectin-1 involvement in glioma chemoresistance???, Toxicology and Applied Pharmacology, vol.229, issue.2, pp.172-83, 2008.
DOI : 10.1016/j.taap.2008.01.009

L. Mercier, M. Mathieu, V. Haibe-kains, B. Bontempi, G. Mijatovic et al., Knocking Down Galectin 1 in Human Hs683 Glioblastoma Cells Impairs Both Angiogenesis and Endoplasmic Reticulum Stress Responses, Journal of Neuropathology & Experimental Neurology, vol.67, issue.5, pp.456-469, 2008.
DOI : 10.1097/NEN.0b013e318170f892

E. Lee, P. Nichols, D. Spicer, S. Groshen, M. C. Yu et al., GRP78 as a Novel Predictor of Responsiveness to Chemotherapy in Breast Cancer, Cancer Research, vol.66, issue.16, pp.7849-53, 2006.
DOI : 10.1158/0008-5472.CAN-06-1660

H. K. Lee, C. Xiang, S. Cazacu, S. Finniss, G. Kazimirsky et al., GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis, Neuro-Oncology, vol.10, issue.3, pp.236-279, 2008.
DOI : 10.1215/15228517-2008-006

K. Lee, W. Tirasophon, X. Shen, M. Michalak, R. Prywes et al., IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response, Genes & Development, vol.16, issue.4, pp.452-66, 2002.
DOI : 10.1101/gad.964702

A. G. Lerner, J. P. Upton, P. V. Praveen, R. Ghosh, Y. Nakagawa et al., IRE1?? Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress, Cell Metabolism, vol.16, issue.2, pp.250-64, 2012.
DOI : 10.1016/j.cmet.2012.07.007

C. T. Leung and J. S. Brugge, Outgrowth of single oncogene-expressing cells from suppressive epithelial environments, Nature, vol.65, issue.7385, pp.410-413, 2012.
DOI : 10.1038/nature10826

P. P. Liberski, The ultrastructure of oligodendroglioma: personal experience and the review of the literature Association of Polish Neuropathologists and Medical Research Centre, Folia Neuropathologica Polish Academy of Sciences, vol.34, pp.206-211, 1996.

P. P. Liberski, The ultrastructure of glial tumors of astrocytic lineage: a review Folia Neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences, vol.36, pp.161-177, 1998.

W. Lin, Y. Lin, J. Li, H. P. Harding, D. Ron et al., A deregulated integrated stress response promotes interferon-??-induced medulloblastoma, Journal of Neuroscience Research, vol.29, issue.10, pp.1586-1595, 2011.
DOI : 10.1002/jnr.22693

Y. Ma and L. M. Hendershot, The role of the unfolded protein response in tumour development: friend or foe?, Nature Reviews Cancer, vol.10, issue.12, pp.966-77, 2004.
DOI : 10.1016/j.neuint.2004.01.003

M. Macaluso, V. Caracciolo, V. Rizzo, A. Sun, M. Montanari et al., Integrating role of T antigen, Rb2/p130, CTCF and BORIS in mediating non-canonical endoplasmic reticulum-dependent death pathways triggered by chronic ER stress in mouse medulloblastoma, Cell Cycle, vol.26, issue.9, pp.1841-1850, 2012.
DOI : 10.1158/0008-5472.CAN-08-1005

S. N. Manie, J. Lebeau, and E. Chevet, Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 3. Orchestrating the unfolded protein response in oncogenesis: an update, AJP: Cell Physiology, vol.307, issue.10, pp.901-908, 2014.
DOI : 10.1152/ajpcell.00292.2014

M. J. Mann and L. M. Hendershot, UPR activation alters chemosensitivity of tumor cells, Cancer Biology & Therapy, vol.5, issue.7, pp.736-776, 2006.
DOI : 10.4161/cbt.5.7.2969

S. Marada, D. P. Stewart, W. J. Bodeen, Y. Han, and S. K. Ogden, The Unfolded Protein Response Selectively Targets Active Smoothened Mutants, Molecular and Cellular Biology, vol.33, issue.12, pp.2375-2387, 2013.
DOI : 10.1128/MCB.01445-12

A. M. Martin, E. Raabe, C. Eberhart, and K. J. Cohen, Management of Pediatric and Adult Patients with Medulloblastoma, Current Treatment Options in Oncology, vol.31, issue.5, pp.581-594, 2014.
DOI : 10.1007/s11864-014-0306-4

M. Maurel, E. Chevet, J. Tavernier, and S. Gerlo, Getting RIDD of RNA: IRE1 in cell fate regulation, Trends in Biochemical Sciences, vol.39, issue.5, pp.245-54, 2014.
DOI : 10.1016/j.tibs.2014.02.008

R. D. Mccomb and P. C. Burger, Choroid plexus carcinoma: Report of a case with lmmunohistochemical and ultrastructural observations, Cancer, vol.3, issue.3, pp.470-475, 1983.
DOI : 10.1002/1097-0142(19830201)51:3<470::AID-CNCR2820510319>3.0.CO;2-K

N. M. Mhaidat, K. H. Alzoubi, N. Almomani, and O. F. Khabour, Expression of glucose regulated protein 78 (GRP78) determines colorectal cancer response to chemotherapy, Cancer Biomarkers, vol.15, issue.2, pp.197-203, 2015.
DOI : 10.3233/CBM-140454

A. A. Moazzam, N. Wagle, and G. Zada, Recent developments in chemotherapy for meningiomas: a review, Neurosurgical Focus, vol.35, issue.6, p.18, 2013.
DOI : 10.3171/2013.10.FOCUS13341

A. M. Muñoz-mármol, G. Mola, T. Ruiz-larroya, A. Fernández-vasalo, E. Vela et al., Rarity of JC virus DNA sequences and early proteins in human gliomas and medulloblastomas: the controversial role of JC virus in human neurooncogenesis, Neuropathology and Applied Neurobiology, vol.12, issue.2, pp.131-140, 2006.
DOI : 10.1073/pnas.93.7.2690

A. Nasir, R. Othman, L. Storer, D. Onion, A. Lourdasamy et al., BM-23 * Twist1 EXPRESSION CONFIRMS THE ROLE OF AN EMT-LIKE PROCESS IN MEDULLOBLASTOMA METASTASIS, Neuro-Oncology, vol.16, issue.suppl 5, pp.37-37
DOI : 10.1093/neuonc/nou240.23

S. Ninagawa, T. Okada, Y. Sumitomo, S. Horimoto, T. Sugimoto et al., Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway, The Journal of Cell Biology, vol.263, issue.4, pp.775-84, 2015.
DOI : 10.1083/jcb.201504109.dv

Z. Niu, M. Wang, L. Zhou, L. Yao, Q. Liao et al., Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer. Sci Rep, p.16067, 2015.

P. A. Northcott, A. Korshunov, H. Witt, T. Hielscher, C. G. Eberhart et al., Medulloblastoma Comprises Four Distinct Molecular Variants, Journal of Clinical Oncology, vol.29, issue.11, pp.1408-1414, 2011.
DOI : 10.1200/JCO.2009.27.4324

P. A. Northcott, A. Korshunov, S. M. Pfister, and M. D. Taylor, The clinical implications of medulloblastoma subgroups, Nature Reviews Neurology, vol.464, issue.6, pp.340-351, 2012.
DOI : 10.1038/nrneurol.2012.78

I. Novoa, H. Zeng, H. P. Harding, and D. Ron, -Mediated Dephosphorylation of eIF2??, The Journal of Cell Biology, vol.12, issue.128, pp.1011-1033, 2001.
DOI : 10.1101/gad.12.7.982
URL : https://hal.archives-ouvertes.fr/hal-01015258

M. Ogata, S. Hino, A. Saito, K. Morikawa, S. Kondo et al., Autophagy Is Activated for Cell Survival after Endoplasmic Reticulum Stress, Molecular and Cellular Biology, vol.26, issue.24, pp.9220-9251, 2006.
DOI : 10.1128/MCB.01453-06

K. Ozawa, Y. Tsukamoto, O. Hori, Y. Kitao, H. Yanagi et al., Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone, Cancer Res, vol.61, pp.4206-4219, 2001.

J. Pallud, E. Audureau, G. Noel, R. Corns, E. Lechapt-zalcman et al., Long-term results of carmustine wafer implantation for newly diagnosed glioblastomas: a controlled propensity-matched analysis of a French multicenter cohort, Neuro-Oncology, vol.17, issue.12, pp.1609-1619, 2015.
DOI : 10.1093/neuonc/nov126
URL : https://hal.archives-ouvertes.fr/hal-01275524

O. Pluquet, N. Dejeans, M. Bouchecareilh, S. Lhomond, R. Pineau et al., Posttranscriptional Regulation of PER1 Underlies the Oncogenic Function of IRE??, Cancer Research, vol.73, issue.15, pp.4732-4775, 2013.
DOI : 10.1158/0008-5472.CAN-12-3989

S. Proulx-bonneau, J. Pratt, and B. Annabi, A role for MT1-MMP as a cell death sensor/effector through the regulation of endoplasmic reticulum stress in U87 glioblastoma cells, Journal of Neuro-Oncology, vol.94, issue.1, pp.33-43, 2011.
DOI : 10.1007/s11060-010-0468-2

P. Pyrko, A. H. Schonthal, F. M. Hofman, T. C. Chen, and A. S. Lee, The Unfolded Protein Response Regulator GRP78/BiP as a Novel Target for Increasing Chemosensitivity in Malignant Gliomas, Cancer Research, vol.67, issue.20, pp.9809-9825, 2007.
DOI : 10.1158/0008-5472.CAN-07-0625

Q. A. Quick and M. O. Faison, CHOP and caspase 3 induction underlie glioblastoma cell death in response to endoplasmic reticulum stress. Experimental and Therapeutic Medicine, pp.487-492, 2012.

M. S. Raab, I. Breitkreutz, G. Tonon, J. Zhang, P. J. Hayden et al., Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling, Blood, vol.113, issue.7, pp.1513-1521, 2009.
DOI : 10.1182/blood-2008-05-157040

C. H. Rickert and W. Paulus, Tumors of the choroid plexus, Microscopy Research and Technique, vol.32, issue.1, pp.104-111, 2001.
DOI : 10.1002/1097-0029(20010101)52:1<104::AID-JEMT12>3.0.CO;2-3

K. M. Rouschop, T. Van-den-beucken, L. Dubois, H. Niessen, J. Bussink et al., The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5, Journal of Clinical Investigation, vol.120, issue.1, pp.127-168, 2010.
DOI : 10.1172/JCI40027DS1

D. Scheuner, B. Song, E. Mcewen, C. Liu, R. Laybutt et al., Translational Control Is Required for the Unfolded Protein Response and In Vivo Glucose Homeostasis, Molecular Cell, vol.7, issue.6, pp.1165-76, 2001.
DOI : 10.1016/S1097-2765(01)00265-9

D. M. Schewe and J. A. Aguirre-ghiso, ATF6??-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo, Proceedings of the National Academy of Sciences, vol.105, issue.30, pp.10519-10543, 2008.
DOI : 10.1073/pnas.0800939105

U. Schubert, L. C. Anton, J. Gibbs, C. C. Norbury, J. W. Yewdell et al., Rapid degradation of a large fraction of newly synthesized proteins by proteasomes, Nature, vol.404, pp.770-774, 2000.

P. Scriven, S. Coulson, R. Haines, S. Balasubramanian, S. Cross et al., Activation and clinical significance of the unfolded protein response in breast cancer, British Journal of Cancer, vol.8, issue.10, 2009.
DOI : 10.1007/s10585-006-9051-9

J. Shen, X. Chen, L. Hendershot, and R. Prywes, ER Stress Regulation of ATF6 Localization by Dissociation of BiP/GRP78 Binding and Unmasking of Golgi Localization Signals, Developmental Cell, vol.3, issue.1, pp.99-111, 2002.
DOI : 10.1016/S1534-5807(02)00203-4

X. Sheng, Y. J. Arnoldussen, M. Storm, M. Tesikova, H. Z. Nenseth et al., Divergent androgen regulation of unfolded protein response pathways drives prostate cancer, EMBO Molecular Medicine, vol.7, issue.6, pp.788-801, 2015.
DOI : 10.15252/emmm.201404509

N. Sheshadri, J. M. Catanzaro, A. J. Bott, Y. Sun, E. Ullman et al., SCCA1/SERPINB3 Promotes Oncogenesis and Epithelial-Mesenchymal Transition via the Unfolded Protein Response and IL6 Signaling, Cancer Research, vol.74, issue.21, pp.6318-6347, 2014.
DOI : 10.1158/0008-5472.CAN-14-0798

M. Shuda, N. Kondoh, N. Imazeki, K. Tanaka, T. Okada et al., Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis, Journal of Hepatology, vol.38, issue.5, pp.605-619, 2003.
DOI : 10.1016/S0168-8278(03)00029-1

R. Stupp, W. P. Mason, M. J. Van-den-bent, M. Weller, B. Fisher et al., Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma, pp.987-996, 2005.

M. Z. Sun, M. C. Oh, M. E. Ivan, G. Kaur, M. Safaee et al., Current management of choroid plexus carcinomas, Neurosurgical Review, vol.156, issue.2, pp.179-192, 2014.
DOI : 10.1007/s10143-013-0499-1

S. Sun, D. Lee, A. S. Ho, J. K. Pu, X. Q. Zhang et al., Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways, Neuro-Oncology, vol.15, issue.5, pp.562-577, 2013.
DOI : 10.1093/neuonc/not005

K. Tabuchi, O. Yamada, and A. Nishimoto, The ultrastructure of pinealomas, Acta Neuropathologica, vol.209, issue.2, pp.117-127, 1973.
DOI : 10.1007/BF00684834

A. B. Tam, A. C. Koong, and M. Niwa, Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD. Cell Rep, pp.850-858, 2014.
DOI : 10.1016/j.celrep.2014.09.016
URL : http://doi.org/10.1016/j.celrep.2014.09.016

J. Tang, Y. S. Guo, Y. Zhang, X. L. Yu, L. Li et al., CD147 induces UPR to inhibit apoptosis and chemosensitivity by increasing the transcription of Bip in hepatocellular carcinoma, CD147 induces UPR to inhibit apoptosis and chemosensitivity by increasing the transcription of Bip in hepatocellular carcinoma, pp.1779-90, 2012.
DOI : 10.1016/j.cell.2006.01.040

E. Tani and N. Higashi, Intercisternal structures of closely arranged endoplasmic reticulum in human meningioma, Acta Neuropathologica, vol.22, issue.4, pp.291-299, 1973.
DOI : 10.1007/BF00687458

W. Tirasophon, A. A. Welihinda, and R. J. Kaufman, A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian??cells, Genes & Development, vol.12, issue.12, pp.1812-1836, 1998.
DOI : 10.1101/gad.12.12.1812

H. Y. Tsai, Y. F. Yang, A. T. Wu, C. J. Yang, Y. P. Liu et al., Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78, Oncogene, vol.9, issue.41, pp.4921-4952, 2013.
DOI : 10.1038/onc.2012.514

L. Ulianich, C. Garbi, A. S. Treglia, D. Punzi, C. Miele et al., ER stress is associated with dedifferentiation and an epithelial-to-mesenchymal transition-like phenotype in PC Cl3 thyroid cells, Journal of Cell Science, vol.121, issue.4, pp.477-86, 2008.
DOI : 10.1242/jcs.017202

J. P. Upton, L. Wang, D. Han, E. S. Wang, N. E. Huskey et al., IRE1?? Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2, Science, vol.338, issue.6108, pp.818-840, 2012.
DOI : 10.1126/science.1226191

L. Vermeulen and H. J. Snippert, Stem cell dynamics in homeostasis and cancer of the intestine, Nature Reviews Cancer, vol.118, issue.7, pp.468-80, 2014.
DOI : 10.4161/cc.9.8.11198

Z. V. Wang, Y. Deng, N. Gao, Z. Pedrozo, D. L. Li et al., Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway, Cell, vol.156, issue.6, pp.1179-92, 2014.
DOI : 10.1016/j.cell.2014.01.014

S. Yaari-stark, M. Shaked, Y. Nevo-caspi, J. Jacob-hircsh, R. Shamir et al., Ras inhibits endoplasmic reticulum stress in human cancer cells with amplified Myc, International Journal of Cancer. Journal International Du Cancer, vol.126, pp.2268-2281, 2010.

A. Yacoub, H. A. Hamed, J. Allegood, C. Mitchell, S. Spiegel et al., PERK-Dependent Regulation of Ceramide Synthase 6 and Thioredoxin Play a Key Role in mda-7/IL-24-Induced Killing of Primary Human Glioblastoma Multiforme Cells, Cancer Research, vol.70, issue.3, pp.1120-1129, 2010.
DOI : 10.1158/0008-5472.CAN-09-4043

K. Yamamoto, T. Sato, T. Matsui, M. Sato, T. Okada et al., Transcriptional Induction of Mammalian ER Quality Control Proteins Is Mediated by Single or Combined Action of ATF6?? and XBP1, Developmental Cell, vol.13, issue.3, pp.365-76, 2007.
DOI : 10.1016/j.devcel.2007.07.018

J. Ye and C. Koumenis, ATF4, an ER Stress and Hypoxia-Inducible Transcription Factor and its Potential Role in Hypoxia Tolerance and Tumorigenesis, Current Molecular Medicine, vol.9, issue.4, pp.411-417, 2009.
DOI : 10.2174/156652409788167096