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Scientific Significance of Clinically Insignificant FcγRIIIa-V158F Polymorphism

Abstract : Kenkre and colleagues report the absence of correlation between FcγRIIIa-V158F polymorphism and rituximab response in follicular lymphoma patients, a result which is in contrast with prior studies. This discrepancy recalls that many other factors (from the host and from the tumor) may influence the efficacy of rituximab in vivo. Clin Cancer Res; 22(4); 787–9. ©2015 AACR. See related article by Kenkre et al., p. 821
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Submitted on : Thursday, April 7, 2016 - 2:37:55 PM
Last modification on : Friday, May 15, 2020 - 12:22:04 PM

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Guillaume Cartron, Roch Houot, Holbrook E Kohrt. Scientific Significance of Clinically Insignificant FcγRIIIa-V158F Polymorphism. Clinical Cancer Research, American Association for Cancer Research, 2016, 22 (4), pp.787--789. ⟨10.1158/1078-0432.CCR-15-2777⟩. ⟨hal-01299291⟩

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