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Identification of CELF1 RNA targets by CLIP-seq in human HeLa cells

Abstract : The specific interactions between RNA-binding proteins and their target RNAs are an essential level to control gene expression. By combining ultra-violet cross-linking and immunoprecipitation (CLIP) and massive SoliD sequencing we identified the RNAs bound by the RNA-binding protein CELF1, in human HeLa cells. The CELF1 binding sites deduced from the sequence data allow characterizing specific features of CELF1-RNA association. We present therefore the first map of CELF1 binding sites in human cells.
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01304359
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, April 19, 2016 - 4:23:39 PM
Last modification on : Wednesday, October 7, 2020 - 10:10:10 AM

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Olivier Le Tonquèze, Bernhard Gschloessl, Vincent Legagneux, Luc Paillard, Yann Audic. Identification of CELF1 RNA targets by CLIP-seq in human HeLa cells. Genomics Data, Elsevier, 2016, 8, pp.97-103. ⟨10.1016/j.gdata.2016.04.009⟩. ⟨hal-01304359⟩

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