Roles of Deformable Image Registration in Adaptive RT: from Contour Propagation to Dose Monitoring

Antoine Simon (1) , Mohamed Nassef (1) , Bastien Rigaud (1) , Guillaume Cazoulat (1) , Joel Castelli (1, 2) , Caroline Lafond (1, 2) , Oscar Acosta (1) , Pascal Haigron (1) , Renaud De Crevoisier (1, 2)

1 LTSI - Laboratoire Traitement du Signal et de l'Image
2 CRLCC - CRLCC Eugène Marquis

Adaptive radiation therapy (ART) is based on the optimization of the treatment plan during the treatment delivery to compensate for anatomical deformations. Deformable Image Registration (DIR) then constitutes a key step in order to analyze the huge amount of daily or weekly images to provide clinically usefull information. Two main applications of DIR have been developped in ART: delineation propagation and dose accumulation. If delineation propagation is well validated and transfered in the clinic, some challenges remain to address for dose accumulation. In this paper, we review the recent developments of DIR in ART, particularly in prostate and head-and-neck (H&N), with a focus on their evaluation

Keywords: Anatomy; computed-tomography; cone-beam ct; dosimetric consequences; head; neck-cancer; nonrigid registration; prostate-cancer; radiation-therapy; Radiotherapy

Domains: Life Sciences [q-bio]; Bioengineering

Antoine Simon, Mohamed Nassef, Bastien Rigaud, Guillaume Cazoulat, Joel Castelli, et al.. Roles of Deformable Image Registration in Adaptive RT: from Contour Propagation to Dose Monitoring. 2015 37th annual international conference of the IEEE Engineering in Medicine and Biology Society, 2015, Milan, Italy. pp.5215--5218. ⟨hal-01304742⟩