Skip to Main content Skip to Navigation
Journal articles

The role of sub-hippocampal versus hippocampal regions in bitemporal lobe epilepsies

Abstract : Objective We aimed at better delineating the functional anatomical organization of bitemporal lobe epilepsy. Methods We studied the epileptogenic zone (EZ) by quantifying the epileptogenicity of brain structures explored by depth electrodes in patients investigated by stereoelectroencephalography (SEEG). We compared 15 patients with bilateral mesial temporal lobe epilepsy (BTLE) and 15 patients with unilateral mesial temporal lobe epilepsy (UTLE). This quantification was performed using the ‘Epileptogenicity Index’ (EI). Results Age at epilepsy onset, and epilepsy duration, were not statistically different in both groups. UTLE patients more frequently displayed maximal epileptogenicity in hippocampal structures, whereas BTLE patients had maximal values in subhippocampal areas (entorhinal cortex, temporal pole, parahippocampal cortex). Conclusions Our results suggest different organization of the EZ in the two groups. Significance BTLE was associated with more involvement of subhippocampal regions, a result in agreement with known anatomical connections between the two temporal lobes. © 2016 International Federation of Clinical Neurophysiology
Document type :
Journal articles
Complete list of metadatas

Cited literature [37 references]  Display  Hide  Download

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01372353
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, December 6, 2016 - 5:21:15 PM
Last modification on : Friday, March 6, 2020 - 4:29:19 PM
Long-term archiving on: : Tuesday, March 21, 2017 - 7:44:37 AM

File

The role of sub-hippocampal ve...
Files produced by the author(s)

Identifiers

Citation

S. Aubert, F. Bonini, J. Curot, L. Valton, W. Szurhaj, et al.. The role of sub-hippocampal versus hippocampal regions in bitemporal lobe epilepsies. Clinical Neurophysiology, Elsevier, 2016, 127 (9), pp.2992--2999. ⟨10.1016/j.clinph.2016.06.021⟩. ⟨hal-01372353⟩

Share

Metrics

Record views

374

Files downloads

638