Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

M. Hedidi; W. Erb; G. Bentabed-Ababsa; Floris Chevallier; L. Picot; V. Thiéry; S. Bach; S. Ruchaud; T. Roisnel; V. Dorcet; F. Mongin

doi:10.1016/j.tet.2016.08.056

Journal articles

Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

M. Hedidi ^{1, 2} W. Erb ² G. Bentabed-Ababsa ¹ Floris Chevallier ² L. Picot ³ V. Thiéry ³ S. Bach ⁴ S. Ruchaud ⁴ T. Roisnel ² V. Dorcet ² F. Mongin ²

1 Laboratoire de Synthèse Organique Appliquée

2 ISCR - Institut des Sciences Chimiques de Rennes

3 LIENSs - LIttoral ENvironnement et Sociétés - UMRi 7266

4 P3H - Phophorylation de protéines et Pathologies Humaines

Keywords : Antiproliferative activity Copper N-Arylation Azole Pyridine

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Journal articles

Domain :

Chemical Sciences / Medicinal Chemistry

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Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

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Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

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