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Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells

M. Hedidi 1, 2 W. Erb 2 G. Bentabed-Ababsa 1 Floris Chevallier 2 L. Picot 3 V. Thiéry 3 S. Bach 4 S. Ruchaud 4 T. Roisnel 2 V. Dorcet 2 F. Mongin 2
1 Laboratoire de Synthèse Organique Appliquée
2 ISCR - Institut des Sciences Chimiques de Rennes
3 LIENSs - LIttoral ENvironnement et Sociétés - UMRi 7266
4 P3H - Phophorylation de protéines et Pathologies Humaines
Keywords : Antiproliferative activity Copper N-Arylation Azole Pyridine
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Submitted on : Wednesday, November 9, 2016 - 9:43:48 AM
Last modification on : Tuesday, October 19, 2021 - 6:23:03 PM
Long-term archiving on: : Tuesday, March 14, 2017 - 10:01:01 PM

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M. Hedidi, W. Erb, G. Bentabed-Ababsa, Floris Chevallier, L. Picot, et al.. Synthesis of N-pyridyl azoles using a deprotometalation-iodolysis-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells. Tetrahedron, Elsevier, 2016, 72 (41), pp.6467--6476. ⟨10.1016/j.tet.2016.08.056⟩. ⟨hal-01381138⟩

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