Hsp90 directly interacts, in vitro, with amyloid structures and modulates their assembly and disassembly

C. Schirmer (1, 2) , E. Lepvrier (1, 3) , Laurence Duchesne (1) , O. Decaux (1, 4) , D. Thomas (1) , C. Delamarche (1) , C. Garnier (1, 5)

1 IGDR - Institut de Génétique et Développement de Rennes
2 JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837
3 OSS - Oncogenesis Stress Signaling
4 CHU Pontchaillou [Rennes]
5 MMDN - Mécanismes moléculaires dans les démences neurodégénératives

Keywords: Ac-VQIVYK-NH(2) peptide; Chaperones; Hsp90; Fibrils; Amyloid proteins

Domains: Life Sciences [q-bio]; Cancer

C. Schirmer, E. Lepvrier, Laurence Duchesne, O. Decaux, D. Thomas, et al.. Hsp90 directly interacts, in vitro, with amyloid structures and modulates their assembly and disassembly. Biochimica et Biophysica Acta (BBA) - General Subjects, 2016, 1860 (11), pp.2598--2609. ⟨10.1016/j.bbagen.2016.07.033⟩. ⟨hal-01381400⟩