Hydrogenation of Carbonyl Derivatives with a Well-Defined Rhenium Precatalyst

Duo Wei (1) , Thierry Roisnel (1) , Christophe Darcel (1) , Eric Clot (2) , Jean-Baptiste Sortais (1)

1 ISCR - Institut des Sciences Chimiques de Rennes
2 ICGM - Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier

The first efficient and general rhenium-catalyzed hydrogenation of carbonyl derivatives was developed. The key to the success of the reaction was the use of a well-defined rhenium complex bearing a tridentate diphosphinoamino ligand as the catalyst (0.5 mol %) at 70 °C in the presence of H2 (30 bar). The mechanism of the reaction was investigated by DFT(PBE0-D3) calculations.

Keywords: reaction mechanisms; rhenium; density functional calculations; hydrogenation; ketones

Domains: Life Sciences [q-bio]

Duo Wei, Thierry Roisnel, Christophe Darcel, Eric Clot, Jean-Baptiste Sortais. Hydrogenation of Carbonyl Derivatives with a Well-Defined Rhenium Precatalyst. ChemCatChem, 2017, 9 (1), pp.80-83. ⟨10.1002/cctc.201601141⟩. ⟨hal-01435008⟩