Skip to Main content Skip to Navigation
Journal articles

One-Pot Directing Group Formation/C-H Bond Functionalization via Copper(I) and Ruthenium(II) Catalysis

Abstract : A copper(I)-catalyzed oxidation leading to the formation of 2-pyridyl ketone directing groups has been efficiently coupled with a ruthenium(II)-catalyzed C(sp(2))-H bond arylation transformation without performing any intermediate work-up. This sustainable approach was further extended to sequential three-step transition metal-catalyzed transformations in which up to four new bonds (C-O, C-C, C-H and O-H) are formed in a one-pot fashion. This is the first example in which two different transition metal catalysts are sequentially employed for the directing group formation and the C-H bond functionalization, respectively.
Document type :
Journal articles
Complete list of metadatas

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01438120
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, January 17, 2017 - 2:50:12 PM
Last modification on : Friday, July 10, 2020 - 4:00:48 PM

Links full text

Identifiers

Citation

Christian Bruneau, Rafael Gramage-Doria. One-Pot Directing Group Formation/C-H Bond Functionalization via Copper(I) and Ruthenium(II) Catalysis. Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2016, 358 (23), pp.3847--3856. ⟨10.1002/adsc.201600735⟩. ⟨hal-01438120⟩

Share

Metrics

Record views

194