18F-Choline Uptake in Acute Ischemic Stroke

Kostas Delaunay (1) , Florence Le Jeune (1) , Etienne Garin (2, 1) , Anne Devillers (3, 1) , Xavier Palard-Novello (1)

1 CRLCC - CRLCC Eugène Marquis
2 Foie, métabolismes et cancer
3 Département de médecine nucléaire [Rennes]

A 75-year-old man with a history of prostate cancer was referred to our department to perform F-choline (FCH) PET/CT. FCH PET/CT showed a markedly increased uptake in the right temporoparietal junction brain. Three weeks earlier, acute ischemic stroke was diagnosed in the right temporoparietal junction brain on diffusion-weighted sequence and thrombosis in a distal branch of the right middle cerebral artery on MR angiography. Choline precursors promote repair and growth of cell membranes in neurologic diseases, so FCH PET/CT uptake could be explained by repair processes during early outcome of acute ischemic stroke.

Domains: Life Sciences [q-bio]; Cancer; Life Sciences [q-bio]; Human health and pathology; Hépatology and Gastroenterology

Kostas Delaunay, Florence Le Jeune, Etienne Garin, Anne Devillers, Xavier Palard-Novello. 18F-Choline Uptake in Acute Ischemic Stroke. Clinical Nuclear Medicine, 2017, 42 (2), pp.e121-e122. ⟨10.1097/RLU.0000000000001439⟩. ⟨hal-01447068⟩