Production of the Non-apoptotic Metalloprotease-Cleaved CD95L and Its Cytotoxic Recombinant Counterpart Designed Ig-CD95L - Archive ouverte HAL Access content directly
Book Sections Year : 2017

Production of the Non-apoptotic Metalloprotease-Cleaved CD95L and Its Cytotoxic Recombinant Counterpart Designed Ig-CD95L

(1, 2) , (1, 2) , (1, 2)
1
2

Abstract

The ligand of CD95, CD95L (also known as FasL or CD178), is a type II transmembrane protein that belongs to the Tumor Necrosis factor (TNF) family (Fig. 1a). This membrane-bound cytokine is mainly expressed at the surface of activated T lymphocytes and natural killer cells, where it is used as an apoptotic factor to eliminate infected and transformed cells (Strasser et al., Immunity 30:180-192, 2009).
Not file

Dates and versions

hal-01447228 , version 1 (26-01-2017)

Identifiers

Cite

Eléonore Lepvrier, Sophie Martin, Brigitte Collet. Production of the Non-apoptotic Metalloprotease-Cleaved CD95L and Its Cytotoxic Recombinant Counterpart Designed Ig-CD95L. CD95: Methods and Protocols, 1557, pp.1-10, 2017, Methods in Molecular Biology, ⟨10.1007/978-1-4939-6780-3_1⟩. ⟨hal-01447228⟩
30 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More