Skip to Main content Skip to Navigation
Journal articles

Interprétation des tests sérologiques : ne pas oublier le transfert passif des immunoglobulines ! [Beware of immunoglobulin's passive transfer when interpreting serological analyses!].

Résumé : Due to their extended indications, intravenous immunoglobulins (IVIg) are increasingly used in hospital setting. After injection, classical IVIg half-life reaches more than 3weeks. IVIg result from the pooling of many blood donations and contain all natural antibodies usually found in the general population. Administered antibodies are known to interfere with many diagnostic assays, particularly those used for infectious serology. It is not recommended to perform serological determination after IVIg infusion. It is recommended to keep a delay of at least 4months after IVIg infusion before doing any serological assay; failure to do so will result in misinterpretation of biological findings. Interpretation of any serological test after IVIg administration should be particularly cautious.
Document type :
Journal articles
Complete list of metadatas

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01477208
Contributor : Xavier Chard-Hutchinson <>
Submitted on : Monday, February 27, 2017 - 10:38:55 AM
Last modification on : Thursday, August 20, 2020 - 3:05:33 AM

Identifiers

Citation

Laëtitia Pinte, Julie Vergez, Amelie Liou, Jean-Marc Léger, Vincent Thibault. Interprétation des tests sérologiques : ne pas oublier le transfert passif des immunoglobulines ! [Beware of immunoglobulin's passive transfer when interpreting serological analyses!].. La Presse Médicale, Elsevier Masson, 2016, 45 (7-8), pp.676-681. ⟨10.1016/j.lpm.2016.03.009⟩. ⟨hal-01477208⟩

Share

Metrics

Record views

185