Rapid transcriptional plasticity of duplicated gene clusters enables a clonally reproducing aphid to colonise diverse plant species - Archive ouverte HAL Access content directly
Journal Articles Genome Biology Year : 2017

Rapid transcriptional plasticity of duplicated gene clusters enables a clonally reproducing aphid to colonise diverse plant species

(1, 2) , (1, 2) , (1) , (3, 2, 4) , (1, 2) , (2, 5) , (2, 4, 3) , (1) , (2, 5) , (3) , (1) , (6) , (2, 7) , (2, 8, 9, 10) , (1) , (2, 8, 10) , (1) , (1) , (11) , (1) , (1) , (10, 2, 8) , (1) , (2, 12) , (1) , (2, 7) , (1, 4) , (2, 13) , (2, 13) , (1) , (2, 14) , (2, 4) , (2, 7) , (15) , (1, 2, 15) , (1, 2, 15)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15

Abstract

BACKGROUND: The prevailing paradigm of host-parasite evolution is that arms races lead to increasing specialisation via genetic adaptation. Insect herbivores are no exception and the majority have evolved to colonise a small number of closely related host species. Remarkably, the green peach aphid, Myzus persicae, colonises plant species across 40 families and single M. persicae clonal lineages can colonise distantly related plants. This remarkable ability makes M. persicae a highly destructive pest of many important crop species. RESULTS: To investigate the exceptional phenotypic plasticity of M. persicae, we sequenced the M. persicae genome and assessed how one clonal lineage responds to host plant species of different families. We show that genetically identical individuals are able to colonise distantly related host species through the differential regulation of genes belonging to aphid-expanded gene families. Multigene clusters collectively upregulate in single aphids within two days upon host switch. Furthermore, we demonstrate the functional significance of this rapid transcriptional change using RNA interference (RNAi)-mediated knock-down of genes belonging to the cathepsin B gene family. Knock-down of cathepsin B genes reduced aphid fitness, but only on the host that induced upregulation of these genes. CONCLUSIONS: Previous research has focused on the role of genetic adaptation of parasites to their hosts. Here we show that the generalist aphid pest M. persicae is able to colonise diverse host plant species in the absence of genetic specialisation. This is achieved through rapid transcriptional plasticity of genes that have duplicated during aphid evolution.
Fichier principal
Vignette du fichier
Rapid transcriptional plasticity of duplicated- version of record.pdf (4.38 Mo) Télécharger le fichier
Vignette du fichier
Erratum.pdf (228.21 Ko) Télécharger le fichier
Origin : Publisher files allowed on an open archive
Origin : Files produced by the author(s)
Loading...

Dates and versions

hal-01500475 , version 1 (02-06-2017)

Licence

Attribution - ShareAlike - CC BY 4.0

Identifiers

Cite

Thomas C. Mathers, Yazhou Chen, Gemy Kaithakottil, Fabrice Legeai, Sam T. Mugford, et al.. Rapid transcriptional plasticity of duplicated gene clusters enables a clonally reproducing aphid to colonise diverse plant species. Genome Biology, 2017, 18 (1), pp.27. ⟨10.1186/s13059-016-1145-3⟩. ⟨hal-01500475⟩
3430 View
375 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More