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Optimization of 18 F-Choline PET/CT acquisition in prostate cancer: Preliminary results concerning the length of the acquisition

Abstract : Objective FCH-PET/CT protocol for prostate cancer assessment consists of an early and late acquisition. Concerning the early acquisition, this study compares contrast-to-noise ratio of tumoral lesions between 5 and 10 minutes post-injection in order to shorten the time of this early acquisition. Materials and methods Patients with proven prostate cancer referred for initial staging or recurrence were prospectively included. Patients underwent 10 minutes of pelvic dynamic acquisition for the early phase and late phase was performed at 60 minutes post-injection. Contrast-to-noise of lesions at 5 and 10 min post-injection were compared. Results Forty-nine patients with 77 lesions were analyzed. No significant difference of prostatic lesions contrast-to-noise ratio was found between 5 min and 10 min post-injection (median contrast-to-noise ratio was respectively 38 and 42, P = 0.128). Conclusion These results could have an impact on clinical practice with FCH-PET/CT early acquisition shortened to 5 min post-injection for patients with prostate cancer.
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01508420
Contributor : Laurent Jonchère <>
Submitted on : Friday, April 14, 2017 - 10:16:28 AM
Last modification on : Tuesday, September 24, 2019 - 2:02:07 PM

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X. Palard-Novello, P. Bourguet, D. Bourhis, F. Le Jeune, E. Garin, et al.. Optimization of 18 F-Choline PET/CT acquisition in prostate cancer: Preliminary results concerning the length of the acquisition. Médecine Nucléaire, Elsevier/Masson, 2017, 41 (1), pp.15-20. ⟨10.1016/j.mednuc.2017.01.003⟩. ⟨hal-01508420⟩

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