P2X Receptors and Inflammation, Current Medicinal Chemistry, vol.22, issue.7, pp.866-77, 2015. ,
DOI : 10.2174/0929867322666141210155311
Receptor in Lung Inflammation and Fibrosis, American Journal of Respiratory and Critical Care Medicine, vol.182, issue.6, pp.774-83, 2010. ,
DOI : 10.1164/rccm.201003-0359OC
URL : https://hal.archives-ouvertes.fr/hal-00591486
The His155Tyr (489C>T) single nucleotide polymorphism of P2RX7 gene confers an enhanced function of P2X7 receptor in immune cells from patients with rheumatoid arthritis, Cellular Immunology, vol.276, issue.1-2, pp.168-175, 2012. ,
DOI : 10.1016/j.cellimm.2012.05.005
P2X7R: A potential key regulator of acute gouty arthritis, Seminars in Arthritis and Rheumatism, vol.43, issue.3, pp.376-380, 2013. ,
DOI : 10.1016/j.semarthrit.2013.04.007
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells, Nature Medicine, vol.118, issue.8, pp.913-919, 2007. ,
DOI : 10.4049/jimmunol.174.12.7725
Purinergic Signaling in Healthy and Diseased Skin, Journal of Investigative Dermatology, vol.132, issue.3, pp.526-546, 2012. ,
DOI : 10.1038/jid.2011.344
URL : http://doi.org/10.1038/jid.2011.344
receptor antagonists ease the pain, British Journal of Pharmacology, vol.1052, issue.5, pp.565-567, 2007. ,
DOI : 10.1152/physrev.00015.2002
Unique Functional Properties of a Sensory Neuronal P2X ATP-Gated Channel from Zebrafish, Journal of Neurochemistry, vol.49, issue.4, pp.1600-1607, 2000. ,
DOI : 10.1016/S0022-2836(05)80360-2
Cryopyrin activates the inflammasome in response to toxins and ATP, Nature, vol.46, issue.7081, pp.228-232, 2006. ,
DOI : 10.4049/jimmunol.173.10.6338
Alerting and tuning the immune response by extracellular nucleotides, Journal of Leukocyte Biology, vol.73, issue.3, pp.339-343, 2003. ,
DOI : 10.1189/jlb.0802418
Adenosine 5???-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation, Pharmacology & Therapeutics, vol.112, issue.2, pp.358-404, 2006. ,
DOI : 10.1016/j.pharmthera.2005.04.013
Role of Pannexin-1 hemichannels and purinergic receptors in 17 ,
Signaling at Purinergic P2X Receptors, Annual Review of Physiology, vol.71, issue.1, pp.333-359, 2009. ,
DOI : 10.1146/annurev.physiol.70.113006.100630
Receptors for purines and pyrimidines, Pharmacol. Rev, vol.50, pp.413-492, 1998. ,
Immune cell regulation by autocrine purinergic signalling, Nature Reviews Immunology, vol.3, issue.3, pp.201-212, 2011. ,
DOI : 10.1371/journal.pone.0002599
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209705
Purinergic receptors in airway epithelia, Current Opinion in Pharmacology, vol.9, issue.3, pp.262-267, 2009. ,
DOI : 10.1016/j.coph.2009.02.004
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692813
The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine, Cell Death and Disease, vol.2, issue.2, p.1629, 2015. ,
DOI : 10.4049/jimmunol.0803154
URL : https://hal.archives-ouvertes.fr/hal-01128180
Immunity, inflammation and cancer: a leading role for adenosine, Nature Reviews Cancer, vol.189, issue.12, pp.842-857, 2013. ,
DOI : 10.4049/jimmunol.1200744
Purinoceptors: Are there families of P2X and P2Y purinoceptors?, Pharmacology & Therapeutics, vol.64, issue.3, pp.445-475, 1994. ,
DOI : 10.1016/0163-7258(94)00048-4
Overview of the P2 Receptors, Seminars in Thrombosis and Hemostasis, vol.31, issue.02, pp.139-149, 2005. ,
DOI : 10.1055/s-2005-869519
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance, Nature, vol.127, issue.7261, pp.282-286, 2009. ,
DOI : 10.1016/S0167-4781(01)00291-3
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851546
Adenosine Triphosphate Induced P2Y2 Receptor Activation Induces Proinflammatory Cytokine Release in Uroepithelial Cells, The Journal of Urology, vol.188, issue.6, pp.2419-2425, 2012. ,
DOI : 10.1016/j.juro.2012.07.095
ATP-gated P2X cation-channels, Neuropharmacology, vol.56, issue.1, pp.208-215, 2009. ,
DOI : 10.1016/j.neuropharm.2008.06.067
Purine and pyrimidine receptors, Cellular and Molecular Life Sciences, vol.64, issue.12, pp.1471-1483, 2007. ,
DOI : 10.1007/s00018-007-6497-0
P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels, The EMBO Journal, vol.17, issue.11, pp.3016-3044, 1998. ,
DOI : 10.1093/emboj/17.11.3016
Evidence for Functional P2X4/P2X7 Heteromeric Receptors, Molecular Pharmacology, vol.72, issue.6, pp.1447-1456, 2007. ,
DOI : 10.1124/mol.107.035980
URL : http://molpharm.aspetjournals.org/content/molpharm/72/6/1447.full.pdf
Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds, Nature Neuroscience, vol.2, issue.4, pp.322-330, 1999. ,
DOI : 10.1038/7233
P2X receptors as cell-surface ATP sensors in health and disease, Nature, vol.279, issue.7102, pp.527-532, 2006. ,
DOI : 10.4049/jimmunol.168.12.6436
Heteromeric assembly of P2X subunits, Frontiers in Cellular Neuroscience, vol.7, p.250, 2013. ,
DOI : 10.3389/fncel.2013.00250
URL : http://journal.frontiersin.org/article/10.3389/fncel.2013.00250/pdf
The P2X7 Receptor: A Key Player in IL-1 Processing and Release, The Journal of Immunology, vol.176, issue.7, pp.3877-83, 2006. ,
DOI : 10.4049/jimmunol.176.7.3877
P2X ion channel receptors and inflammation, Purinergic Signalling, vol.87, issue.1, pp.59-67, 2016. ,
DOI : 10.1152/physrev.00043.2006
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749528
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems, Int. Rev. Cytol, vol.240, pp.31-304, 2004. ,
DOI : 10.1016/S0074-7696(04)40002-3
Pharmacology of P2X channels, Pfl??gers Archiv - European Journal of Physiology, vol.120, issue.23, pp.513-537, 2006. ,
DOI : 10.1113/jphysiol.1996.sp021722
The Cytolytic P2Z Receptor for Extracellular ATP Identified as a P2X Receptor (P2X7), Science, vol.272, issue.5262, pp.735-738, 1996. ,
DOI : 10.1126/science.272.5262.735
A Functional P2X7 Splice Variant with an Alternative Transmembrane Domain 1 Escapes Gene Inactivation in P2X7 Knock-out Mice, Journal of Biological Chemistry, vol.177, issue.38, pp.25813-25822, 2009. ,
DOI : 10.4049/jimmunol.0900120
Proteomic and functional evidence for a P2X7 receptor signalling complex, The EMBO Journal, vol.20, issue.22, pp.6347-6358, 2001. ,
DOI : 10.1093/emboj/20.22.6347
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125721
Extracellular ATP4? promotes cation fluxes in the J774 mouse macrophage cell line, J. Biol. Chem, vol.262, pp.3118-3140, 1987. ,
receptor death complex, FEBS Letters, vol.58, issue.3, pp.483-488, 2007. ,
DOI : 10.1080/15216540600794526
Involvement of purinergic receptors and NOD-like receptor-family protein 3-inflammasome pathway in the adenosine triphosphate-induced cytokine release from macrophages, Clinical and Experimental Pharmacology and Physiology, vol.15, issue.4, pp.279-286, 2014. ,
DOI : 10.1016/S1074-7613(01)00229-1
URL : https://hal.archives-ouvertes.fr/hal-01134782
L???inflammasome NLRP3??: physiopathologie et application th??rapeutique, La Presse M??dicale, vol.45, issue.4, pp.438-446, 2016. ,
DOI : 10.1016/j.lpm.2016.01.006
Gout-associated uric acid crystals activate the NALP3 inflammasome, Nature, vol.20, issue.7081, pp.237-241, 2006. ,
DOI : 10.7326/0003-4819-62-4-648
URL : http://www.nature.com/nature/journal/v440/n7081/pdf/nature04516.pdf
Inflammasomes: current understanding and open questions, Cellular and Molecular Life Sciences, vol.284, issue.5, pp.765-783, 2011. ,
DOI : 10.1074/jbc.M806084200
Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome, The Journal of Immunology, vol.187, issue.2, pp.613-617, 2011. ,
DOI : 10.4049/jimmunol.1100613
The NLRP3 Inflammasome: A Sensor for Metabolic Danger?, Science, vol.284, issue.31, pp.296-300, 2010. ,
DOI : 10.1074/jbc.M109.023689
Uric Acid Is a Danger Signal Activating NALP3 Inflammasome in Lung Injury Inflammation and Fibrosis, American Journal of Respiratory and Critical Care Medicine, vol.179, issue.10, pp.903-913, 2009. ,
DOI : 10.1164/rccm.200808-1274OC
URL : https://hal.archives-ouvertes.fr/hal-00404885
Ivermectin-dependent release of IL-1beta in response to ATP by peritoneal macrophages from P2X(7)-KO mice, Purinergic Signal, vol.4, pp.405-416, 2010. ,
P2Y6 Receptor Signaling Pathway Mediates Inflammatory Responses Induced by Monosodium Urate Crystals, The Journal of Immunology, vol.188, issue.1, pp.436-444, 2012. ,
DOI : 10.4049/jimmunol.1003746
URL : http://www.jimmunol.org/content/jimmunol/188/1/436.full.pdf
Effect of the Purinergic Inhibitor Oxidized ATP in a Model of Islet Allograft Rejection, Diabetes, vol.62, issue.5, pp.1665-1675, 2013. ,
DOI : 10.2337/db12-0242
Advance in the research on P2X7 and inflammatory respiratory diseases, Yao Xue Xue Bao, vol.48, pp.1183-1188, 2013. ,
Involvement of the P2X7 purinergic receptor in inflammation: an update of antagonists series since, p.20, 2009. ,
Promising Therapeutic Potential of P2X7 Modulators, ACS Medicinal Chemistry Letters, vol.7, issue.4, pp.348-350, 2016. ,
DOI : 10.1021/acsmedchemlett.6b00083
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834659
IL-1?? production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages, The FASEB Journal, vol.29, issue.10, pp.4162-4173, 2015. ,
DOI : 10.1096/fj.14-267393
Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions, Immunologic Research, vol.278, issue.1, pp.22-38, 2011. ,
DOI : 10.1074/jbc.M212759200
Involvement of matrix metalloproteinases (MMPs) and inflammasome pathway in molecular mechanisms of fibrosis, Bioscience Reports, vol.36, issue.4, p.20160107, 2016. ,
DOI : 10.1042/BSR20160107
URL : https://hal.archives-ouvertes.fr/hal-01373301
Idiopathic Pulmonary Fibrosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy, Annals of Internal Medicine, vol.134, issue.2, pp.136-151, 2001. ,
DOI : 10.7326/0003-4819-134-2-200101160-00015
Idiopathic Pulmonary Fibrosis, American Journal of Respiratory and Critical Care Medicine, vol.157, issue.4, pp.1301-1315, 1998. ,
DOI : 10.1164/ajrccm.157.4.9707039
Lung Inflammation and Fibrosis, American Journal of Respiratory and Critical Care Medicine, vol.157, issue.4, pp.157-123, 1998. ,
DOI : 10.1164/ajrccm.157.4.nhlbi-10
Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmonary fibrosis, Respiratory Research, vol.191, issue.1, p.14, 2016. ,
DOI : 10.1164/rccm.201406-1106LE
Pharmacological treatment of idiopathic pulmonary fibrosis ??? preclinical and clinical studies of pirfenidone, nintedanib, and N-acetylcysteine, European Clinical Respiratory Journal, vol.62, issue.1, p.26385, 2015. ,
DOI : 10.1016/S1734-1140(10)70250-4
Real World Experiences: Pirfenidone and Nintedanib are Effective and Well Tolerated Treatments for Idiopathic Pulmonary Fibrosis, Journal of Clinical Medicine, vol.31, issue.9, p.9, 2016. ,
DOI : 10.1111/resp.12297
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039481
Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis, Respiratory Research, vol.25, issue.3, p.157, 2014. ,
DOI : 10.1016/j.cytogfr.2014.03.003
Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis, Pulmonary Pharmacology & Therapeutics, vol.40, pp.95-103, 2016. ,
DOI : 10.1016/j.pupt.2016.07.009
Cellular Mechanisms of Tissue Fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosis, AJP: Cell Physiology, vol.306, issue.9, pp.306-779, 2014. ,
DOI : 10.1152/ajpcell.00381.2013
Liver fibrosis ??? from bench to bedside, Journal of Hepatology, vol.38, pp.38-53, 2003. ,
DOI : 10.1016/S0168-8278(02)00429-4
Inflammasomes in liver diseases, Journal of Hepatology, vol.57, issue.3, pp.642-654, 2012. ,
DOI : 10.1016/j.jhep.2012.03.035
URL : http://doi.org/10.1016/j.jhep.2012.03.035
P2X7 receptor-NADPH oxidase axis mediates protein radical formation and Kupffer cell activation in carbon tetrachloride-mediated steatohepatitis in obese mice, Free Radical Biology and Medicine, vol.52, issue.9, pp.1666-1679, 2012. ,
DOI : 10.1016/j.freeradbiomed.2012.02.010
P2X7 blockade attenuates mouse liver fibrosis, Molecular Medicine Reports, vol.9, issue.1, pp.57-62, 2014. ,
DOI : 10.3892/mmr.2013.1807
P2X7 Receptor as a Key Player in Oxidative Stress-Driven Cell Fate in Nonalcoholic Steatohepatitis, Oxidative Medicine and Cellular Longevity, vol.182, issue.4, p.172493, 2015. ,
DOI : 10.1038/ni.1980
1 Gene to Lungs of ???Fibrosis-prone??? and ???Fibrosis-resistant??? Mouse Strains, American Journal of Respiratory Cell and Molecular Biology, vol.27, issue.2, pp.141-150, 2002. ,
DOI : 10.1165/ajrcmb.27.2.4674
P2Y12 Receptor Antagonists: Which One to Choose? A Systematic Review and Meta-Analysis, Current Pharmaceutical Design, vol.22, issue.29, 2016. ,
DOI : 10.2174/1381612822666160608114424
results in resistance to contact hypersensitivity, The Journal of Experimental Medicine, vol.163, issue.12, pp.2609-2619, 2010. ,
DOI : 10.1038/sj.jid.5700819
The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1???? knockout mice, Behavioural Brain Research, vol.204, issue.1, pp.77-81, 2009. ,
DOI : 10.1016/j.bbr.2009.05.018
Targeting interleukin-1 signaling in chronic inflammation: focus on P2X(7) receptor and Pannexin-1, Drug News Perspect, vol.21, pp.424-433, 2008. ,
A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases, Expert Opinion on Investigational Drugs, vol.12, issue.7, pp.897-915, 2011. ,
DOI : 10.1007/s11302-009-9141-7
Purinergic receptor P2X7: A novel target for anti-inflammatory therapy, Bioorganic & Medicinal Chemistry, vol.22, issue.1, pp.54-88, 2014. ,
DOI : 10.1016/j.bmc.2013.10.054
purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine, Annals of the Rheumatic Diseases, vol.71, issue.10, pp.1630-1635, 2012. ,
DOI : 10.1136/annrheumdis-2011-143578
Efficacy and Safety of CE-224,535, an Antagonist of P2X7 Receptor, in Treatment of Patients with Rheumatoid Arthritis Inadequately Controlled by Methotrexate, The Journal of Rheumatology, vol.39, issue.4, pp.720-727, 2012. ,
DOI : 10.3899/jrheum.110874
Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration, AJP: Gastrointestinal and Liver Physiology, vol.299, issue.1, pp.299-331, 2010. ,
DOI : 10.1152/ajpgi.00282.2009
URL : https://hal.archives-ouvertes.fr/hal-00553099
Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer, Cancer Research, vol.75, issue.5, pp.835-845, 2015. ,
DOI : 10.1158/0008-5472.CAN-14-1778
COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord, BMC Neurology, vol.3, issue.1, p.12, 2006. ,
DOI : 10.1016/S1471-4892(02)00004-8
Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimer??s disease, NeuroReport, vol.19, issue.17, pp.1715-1719, 2008. ,
DOI : 10.1097/WNR.0b013e3283179333
P2RX7 Purinoceptor: A Therapeutic Target for Ameliorating the Symptoms of Duchenne Muscular Dystrophy, PLOS Medicine, vol.346, issue.10, p.1001888, 2015. ,
DOI : 10.1371/journal.pmed.1001888.s013
Purinergic signaling in retinal degeneration and regeneration, Neuropharmacology, vol.104, pp.194-211, 2016. ,
DOI : 10.1016/j.neuropharm.2015.05.005
Understanding the roles of the P2X7 receptor in solid tumour progression and therapeutic perspectives, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1848, issue.10, pp.2584-602, 2015. ,
DOI : 10.1016/j.bbamem.2014.10.029