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Journal articles
Early-onset neonatal sepsis is associated with a high heart rate during automatically selected stationary periods
Abstract : AIM: This study examined the heart rate variability characteristics associated with early-onset neonatal sepsis in a prospective, observational controlled study.METHODS: Eligible patients were full-term neonates hospitalised with clinical signs that suggested early-onset sepsis and a C-reactive protein of >10 mg/L. Sepsis was considered proven in cases of symptomatic septicaemia, meningitis, pneumonia or enterocolitis. Heart rate variability parameters (n = 16) were assessed from five-, 15- and 30-minute stationary sequences automatically selected from electrocardiographic recordings performed at admission and compared with a control group using the U-test with post hoc Benjamini-Yekutieli correction. Stationary sequences corresponded to the periods with the lowest changes of heart rate variability over time.RESULTS: A total of 40 full-term infants were enrolled, including 14 with proven sepsis. The mean duration of the cardiac cycle length was lower in the proven sepsis group than in the control group (n = 11), without other significant changes in heart rate variability parameters. These durations, measured in five-minute stationary periods, were 406 (367-433) ms in proven sepsis group versus 507 (463-522) ms in the control group (p < 0.05).CONCLUSION: Early-onset neonatal sepsis was associated with a high mean heart rate measured during automatically selected stationary periods.
Cited literature [23 references]
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01518407
Contributor : Laurent Jonchère <>
Submitted on : Wednesday, July 5, 2017 - 10:19:46 AM
Last modification on : Monday, March 1, 2021 - 3:55:05 PM
Long-term archiving on: : Friday, December 15, 2017 - 3:21:46 AM
Contributor : Laurent Jonchère <>
Submitted on : Wednesday, July 5, 2017 - 10:19:46 AM
Last modification on : Monday, March 1, 2021 - 3:55:05 PM
Long-term archiving on: : Friday, December 15, 2017 - 3:21:46 AM
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Nguyen et al. - 2017 - Early o...
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