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Dysmetabolic iron overload syndrome: a mild but unquestionable iron overload is identified by MRI

Abstract : Castiella et al. claim that liver iron concentration (LIC) is not increased in patients with hyperferritinemia and metabolic syndrome on the basis of a study[1] in which LIC was measured using magnetic resonance imaging (MRI) in 54 patients referred for hyperferritinemia. However, this study has a major limitation, because 5% of patients had viral hepatitis and 35% were excessive drinkers (>40 g/day), two conditions that can induce hyperferritinemia without iron overload.
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Fabrice Lainé, Edouard Bardou-Jacquet, Anita Paisant, Yves Gandon, Yves Deugnier. Dysmetabolic iron overload syndrome: a mild but unquestionable iron overload is identified by MRI. Hepatology, Wiley-Blackwell, 2017, 65 (6), pp.2119-2120. ⟨10.1002/hep.29032⟩. ⟨hal-01531023⟩

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