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New indices of left ventricular function: let's move from ejection fraction to more physiological parameters

Abstract : The assessment of myocardial function in the context of valvular heart disease (VHD) remains highly challenging. The myocardium deforms simultaneously in three-dimensions, and global left ventricular (LV) function parameters such as volume and ejection fraction (EF) may remain compensated despite alterations in myocardial deformation properties. In VHD, the decline in myocardial deformation parameters precedes the onset of symptoms and portends a poor outcome. Nevertheless, it has not been demonstrated that LV global longitudinal strain (GLS) has independent prognostic value in patients with VHD2 and GLS does not figure in current recommendations for the management of these patients
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Submitted on : Wednesday, July 12, 2017 - 7:37:14 PM
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Erwan Donal, Elena Galli, Arnaud Hubert, Guillaume Bouzillé. New indices of left ventricular function: let's move from ejection fraction to more physiological parameters. The Journal of Physiology, Wiley, 2017, 595 (12), pp.3959-3960. ⟨10.1113/JP274108⟩. ⟨hal-01558812⟩

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