Skip to Main content Skip to Navigation
Journal articles

Reactivity of benzofuran and benzothiophene in palladium-catalysed direct C2,C3-diarylations

Abstract : The Pd-catalysed one pot direct diarylation of benzofuran and benzothiophene at both C2- and C3-positions was studied. In the presence of electron-deficient aryl bromides, the diarylation of benzofuran proceeded in good yields; whereas, with benzothiophene moderate yields were generally obtained, as the C3-position exhibits a poor reactivity. In order to obtain 2,3-diarylated benzothiophenes, its sequential arylation was examined. We found that the C3-arylation of benzothiophene followed by its C2-arylation provides a reliable methodology for the access to 2,3-diarylbenzothiophenes.
Document type :
Journal articles
Complete list of metadata

Cited literature [12 references]  Display  Hide  Download
Contributor : Laurent Jonchère <>
Submitted on : Friday, October 13, 2017 - 9:28:00 AM
Last modification on : Friday, July 2, 2021 - 11:57:06 AM
Long-term archiving on: : Sunday, January 14, 2018 - 12:48:04 PM


Reactivity of benzofuran_accep...
Files produced by the author(s)



Karima Si Larbi, Safia Djebbar, Jean-François Soulé, Henri Doucet. Reactivity of benzofuran and benzothiophene in palladium-catalysed direct C2,C3-diarylations. Journal of Organometallic Chemistry, Elsevier, 2017, 843, pp.32-39. ⟨10.1016/j.jorganchem.2017.05.029⟩. ⟨hal-01559209⟩



Record views


Files downloads